FREDERICK H. SILVER

BIOCELL, Vol.46, No.2, pp. 297-299, 2022, DOI:10.32604/biocell.2022.017406 - 20 October 2021

Abstract Gravity plays a central role in vertebrate development and evolution. Mechanotransduction involves the tensile tethering of veins and arteries, connections between the epidermis and dermis in skin, tensile stress concentrations that occur at tissue interfaces, cell-cell interactions, cell-collagen fiber stress transfer in extracellular matrix and fluid shear flow. While attention in the past has been directed at understanding the myriad of biochemical players associated with mechanotransduction pathways, less attention has been focused on determining the tensile mechanical behavior of tissues in vivo. Fibroblasts sit on the surface of collagen fibers in living skin and exert a More >

Huazhe Jiao^1,2, Yachuang Wu¹, Wei Wang^2,*, Xinming Chen¹, Yunfei Wang¹, Juanhong Liu³, Wentao Feng⁴

Journal of Renewable Materials, Vol.9, No.4, pp. 637-650, 2021, DOI:10.32604/jrm.2021.014310 - 01 February 2021

Abstract Higher concentration is beneficial for the Paste and Thickened Tailings (PTT) operation in metal mine. Partial paste thickeners are produced lower density underflow. Flocculated tailings are intended to form a water entrapped network structure in thickener, which is detrimental to underflow concentration. In this study, the continuous thickening experiment was carried out for ultra-fine tungsten tailings to study the influence of rake shearing on underflow. The micro pores structure and seepage flow in tailings bed before and after shearing are studied by CT and simulation approach to reveal the shearing enhancement mechanism of thickening process.… More >

Brenton S. Taft^a,*, Kevin W. Irick^b

Frontiers in Heat and Mass Transfer, Vol.12, pp. 1-7, 2019, DOI:10.5098/hmt.12.24

Abstract On September 7th, 2017 the U.S. Air Force Research Laboratory launched the second Advanced Structurally Embedded Thermal Spreader (ASETSII) flight experiment to space on Orbital Test Vehicle 5. The ASETS-II experiment is made of three low-mass, low-cost oscillating heat pipes (OHPs) and an electronics/experiment control box. The three primary science objectives of the experiment are to measure the initial on-orbit thermal performance, to measure long duration thermal performance, and to assess any lifetime degradation. The three OHPs on ASETS-II are of varying configuration (center heating with single- and double-sided cooling) and working fluids (butane and… More >

Sufang Wang^1,2, Wenjuan Zhao^1,2, Guolin Shi^1,2, Nu Zhang^1,2, Chen Zhang^1,2, Hui Yang^1,2,*

Molecular & Cellular Biomechanics, Vol.16, Suppl.2, pp. 100-100, 2019, DOI:10.32604/mcb.2019.07112

Abstract Long-term space flight will be a major mission for International Space Administration. However, it has been shown that exposure to space flight result in immune system dysfunction. Therefore, understand the mechanism of immune response under microgravity condition is a key topic. Macrophage is one of the most important immune cells in human body, playing key roles in both innate and adaptive immune systems. In this research, we used mouse macrophages (RAW264.7) and collected samples at short-term (8 hour), mediate-term (24 hour) and long-term (48 hour) microgravity treatment. We measured cell proliferation, phagocytosis function and used More >

Jun Du^1,*, Xin Wu¹, Ruonan Li¹, Ranran Cheng¹

FDMP-Fluid Dynamics & Materials Processing, Vol.15, No.1, pp. 77-87, 2019, DOI:10.32604/fdmp.2019.05949

Abstract In this paper, we take the mid-temperature gravity heat pipe exchanger as the research object, simulate the fluid flow field, temperature field and the working state of heat pipe in the heat exchanger by Fluent software. The effects of different operating parameters and fin parameters on the heat transfer performance of heat exchangers are studied. The results show that the heat transfer performance of the mid-temperature gravity heat pipe exchanger is the best when the fin spacing is between 5 mm and 6 mm, the height of the heat pipe is between 12 mm and More >

Kyung Sung Kim¹, Moo-Hyun Kim^2,*, Hakun Jang³, Hee Chen Cho⁴

CMES-Computer Modeling in Engineering & Sciences, Vol.116, No.1, pp. 11-29, 2018, DOI:10.31614/cmes.2018.00199

Abstract A new MPS (Moving Particle Semi-implicit) method is developed to simulate the behaviors and interactions of multiple fine solid particles as a continuum. As fluid particles are affected by viscosity, so solid particles are affected by friction. The solid particle dynamics for landslides, dumping, and gravity sorting etc. which can be difficult to simulate using conventional MPS methods, are modeled in this paper using the developed multi-solid-particle MPS method that benefits from drawing comparisons with the corresponding fluid particle behaviors. The present MPS results for dumping solid particles are verified against the corresponding DEM (Discrete… More >

Noraihan Afiqah Rawi^a , Abdul Rahman Mohd Kasim^b , Zaiton Mat Isa^a , Aurangzaib Mangi^c , Sharidan Shafie^a,*

Frontiers in Heat and Mass Transfer, Vol.8, pp. 1-7, 2017, DOI:10.5098/hmt.8.12

Abstract Mixed convection flows of nanofluid past an inclined stretching sheet with g-jitter effect is studied in this paper. Water based nanofluid containing copper, copper oxide, aluminium oxide and silver nanoparticles are concerned. Coupled nonlinear partial differential equations are solved using Kellerbox method. The effect of solid nanoparticles volume fraction parameter, frequency of oscillation and inclination angle parameter is observed to reduce the skin friction and heat transfer coefficients whereas mixed convection parameter increases both skin friction and heat transfer coefficients. Present study also shows that, the heat transfer coefficient is highest for silver nanofluid. More >

XiangXie^1,a, Deng Liu^1,a, Daoxi Lei¹, Yongfei Liu¹, Qi Wang¹, Zaien Wen¹, Juhui Qiu¹, Dongyu Jia^1,2, Hans Gregersen¹, Guixue Wang^1,*

Molecular & Cellular Biomechanics, Vol.14, No.3, pp. 171-186, 2017, DOI:10.3970/mcb.2017.014.171

Abstract Research in microgravity is of utmost importance for disclosing the impact of gravity on biological processes and organisms. With the development of space technology, scientists pay more attention to cardiovascular diseases associated with microgravity. However, up to date only sparse data exist on microgravity and cardiovascular development mechanisms. In this study, zebrafish was chosen as the model organism. Zebrafish embryos were exposed to microgravity using a ground-based simulation microgravity (SM) bioreactor. The effects of SM on the development of early embryonic vascular system were studied in vivo in real-time. Zebrafish embryos were selected and divided… More >

Kun Zhang^*, Liang Bi Wang

Frontiers in Heat and Mass Transfer, Vol.7, pp. 1-7, 2016, DOI:10.5098/hmt.7.18

Abstract Detailed numerical analysis is presented for the effect of spaceship orbital transfer on solution convection during protein crystal growth under microgravity. The results show that the flow and mass transfer during protein crystal growth are unsteady in the process of orbital transfer. For the case of quasi-steady acceleration, the flow is so weak that the effect of flow on concentration field can be negligible. For the case of position adjustment, the convection is enhanced with protein crystal diameter d_c > 0.2 mm and slightly alters the purely diffusive concentration distribution under zero gravity condition. For the More >

Mingzhi Luo^1,2, Peili Yu¹, Yang Jin³, Zhili Qian¹, Yue Wang¹, Jingjing Li¹, Peng Shang^2*, Linhong Deng^1*

Molecular & Cellular Biomechanics, Vol.13, No.2, pp. 137-157, 2016, DOI:10.3970/mcb.2016.013.155

Abstract Random positioning machine (RPM) and diamagnetic levitation are two essential ground-based methods used to stimulate the effect of microgravity in space life science research. However, the force fields generated by these two methods are fundamentally different, as RPM generates a dynamic force field acting on the surface in contact with supporting substrate, whereas diamagnetic levitation generates a static force field acting on the whole body volume of the object (e.g. cell). Surprisingly, it is hardly studied whether these two fundamentally different force fields would cause different responses in mammalian cells. Thus we exposed cultured MC3T3-E1… More >