MARKO SKELIN^1,2,3,*, BRUNA PERKOV-STIPIČIN¹, SANJA VUŠKOVIĆ⁴, MARINA ŠANDRK PLEHAČEK⁵, ANE BAŠIĆ⁶, DAVID ŠARČEVIĆ⁷, MAJA ILIĆ⁸, IVAN KREČAK^2,3,9

Oncology Research, Vol.32, No.5, pp. 807-815, 2024, DOI:10.32604/or.2024.048948

Abstract Background: The European Society for Medical Oncology (ESMO) guidelines are among the most comprehensive and widely used clinical practice guidelines (CPGs) globally. However, the level of scientific evidence supporting ESMO CPG recommendations has not been systematically investigated. This study assessed ESMO CPG levels of evidence (LOE) and grades of recommendations (GOR), as well as their trends over time across various cancer settings. Methods: We manually extracted every recommendation with the Infectious Diseases Society of America (IDSA) classification from each CPG. We examined the distribution of LOE and GOR in all available ESMO CPG guidelines across different topics and cancer types.… More >

Dahyeon Kim¹, Namgi Kim², Junho Ahn^2,*

CMC-Computers, Materials & Continua, Vol.78, No.3, pp. 3867-3889, 2024, DOI:10.32604/cmc.2024.046871

Abstract This research aims to propose a practical framework designed for the automatic analysis of a product’s comprehensive functionality and security vulnerabilities, generating applicable guidelines based on real-world software. The existing analysis of software security vulnerabilities often focuses on specific features or modules. This partial and arbitrary analysis of the security vulnerabilities makes it challenging to comprehend the overall security vulnerabilities of the software. The key novelty lies in overcoming the constraints of partial approaches. The proposed framework utilizes data from various sources to create a comprehensive functionality profile, facilitating the derivation of real-world security guidelines. Security guidelines are dynamically generated… More >

MIRKO TRECCANI^*, ELENA LOCATELLI, CRISTINA PATUZZO, GIOVANNI MALERBA^*

BIOCELL, Vol.47, No.6, pp. 1225-1241, 2023, DOI:10.32604/biocell.2023.027884

Abstract The advent of genomic big data and the statistical need for reaching significant results have led genome-wide association studies to be ravenous of a huge number of genetic markers scattered along the whole genome. Since its very beginning, the so-called genotype imputation served this purpose; this statistical and inferential procedure based on a known reference panel opened the theoretical possibility to extend association analyses to a greater number of polymorphic sites which have not been previously assayed by the used technology. In this review, we present a broad overview of the genotype imputation process, showing the most known methods and… More >

Alyssia Venna¹, Kathleen Reid², Sarah Davis², Jiaxiang Gai³, Yves d’Udekem¹, Sarah Clauss^2,*

Congenital Heart Disease, Vol.17, No.5, pp. 505-518, 2022, DOI:10.32604/chd.2022.021571

Abstract Background: Patients with single ventricle anatomy are at increased risk of growth failure and malnutrition. Amongst cardiac centers, there is little standardization of feeding practices in this complex population. We hypothesized that initiation of our center’s preoperative feeding protocol would result in decreased gastrostomy tube (G-tube) use, decreased length of stay and would not result in increased Necrotizing Enterocolitis (NEC) rates. Methods: A single institution review of 52 patients who had undergone stage I single ventricle palliative repair was performed. Patient diagnoses were hypoplastic left heart syndrome (39%), atrioventricular canal (15%), and other (46%). Postoperative parameters such as time to… More > Graphic Abstract

Annina Dietrich^1,2, Daniel Quandt^1,2, Oliver Kretschmar^1,2, Walter Knirsch^1,2,*

Congenital Heart Disease, Vol.17, No.2, pp. 215-230, 2022, DOI:10.32604/CHD.2021.017232

Abstract Objectives: To determine immediate and long-term follow-up of transcatheter closure of patent ductus arteriosus (PDA) in children. Background: National antibiotic prophylaxis (AP) guideline for infective endocarditis changed after 2009, the effect on practice of PDA closure is unknown. Methods: Observational single center study analyzing follow-up of PDA closure comparing two time periods before (2002–2009) and after (2010–2019) changes in AP guideline. Results: 332 patients (68.1% female), median (interquartile range) age 3.0 years (1.5–5.7) and body weight 14.0 kg (10.0–19.3), were enrolled. PDA morphology was conical type A (50.3%), window type B (1.2%), tubular type C (40.1%), complex type D (2.1%),… More >

Shaoying Liu^1,2,#, Qian Yu^3,#, Md Mahbub Hossain⁴, Scott Doig⁵, Ran Bao⁶, Yaping Zhao⁷, Jin Yan^8,*, Xun Luo³, Jiaxuan Yang³, Arthur F. Kramer^9,10, Liye Zou³

International Journal of Mental Health Promotion, Vol.24, No.1, pp. 13-24, 2022, DOI:10.32604/IJMHP.2021.017660

Abstract This research is designed to investigate the relationship between the 24-h movement guidelines (24-HMG) and self-reported academic achievement (AA) using nationally representative data derived from the 2019 U.S. National Youth Risk Behaviour Survey. A multiple-stage cluster sampling procedure has been adopted to ensure a representative sample (N = 9127 adolescents; mean age = 15.7 years old; male% = 49.8%). Logistic regression has been adopted to obtain the odds ratio (OR) regarding the associations between adherence to 24-HMG and AA while controlling for ethnicity, body mass index, sex and age. The prevalence of meeting the 24-h movement guidelines in isolation and… More >

Masanori Honda^1,3, Chikara Kawamura^1,3, Isamu Kizaki¹, Yoichi Miyajima¹, Akihiro Takezawa^2,*, Mitsuru Kitamura³

CMES-Computer Modeling in Engineering & Sciences, Vol.128, No.2, pp. 731-742, 2021, DOI:10.32604/cmes.2021.016181

Abstract A body frame composed of thin sheet metal is a crucial structure that determines the safety performance of a vehicle. Designing a correct weight and high-performance automotive body is an emerging engineering problem. To improve the performance of the automotive frame, we attempt to reconstruct its design criteria based on statistical and mechanical approaches. At first, a fundamental study on the frame strength is conducted and a cross-sectional shape optimization problem is developed for designing the cross-sectional shape of an automobile frame having a very high mass efficiency for strength. Shape optimization is carried out using the nonlinear finite element… More >

Qin An¹, Jun Gao², Zhiqin Sang³, Mingyi Qian^4,*

International Journal of Mental Health Promotion, Vol.23, No.1, pp. 87-98, 2021, DOI:10.32604/IJMHP.2021.014422

Abstract When COVID-19 pandemic hit China, Chinese clinical psychologists, counselors and other practitioners reacted quickly to provide psychological interventions for different target groups. Different professional ethical concerns and potential transgressions arose during different stages of pandemic. This paper aimed to summarize different ethical concerns and transgressions during different stages of pandemic in China, as well as how the professional ethical workgroup in the registration system of clinical psychologists and professional organizations of Chinese Psychological Society (CPS) to publish a series of documents as recommendations on ethical practice. It is hoped by providing a picture of “problems vs. solutions” in terms of… More >

Heather Y. Sun¹, James A. Proudfoot², Rachel T. McCandless¹

Congenital Heart Disease, Vol.13, No.5, pp. 748-756, 2018, DOI:10.1111/chd.12648

Abstract Background: Fetal echocardiography can accurately diagnose critical congenital heart disease prenatally, but relies on referrals from abnormalities identified on routine obstetrical ultrasounds. Critical congenital heart disease that is frequently missed due to inadequate outflow tract imaging includes anomalies such as truncus arteriosus, double outlet right ventricle, transposition of the great arteries, tetralogy of Fallot, pulmonary stenosis, and aortic stenosis.
Objective: This study evaluated the prenatal detection rate of critical outflow tract anomalies in a single urban pediatric hospital before and after “AIUM Practice Guideline for the Performance of Obstetric Ultrasound Examinations,” which incorporated outflow tract imaging.
Design: Infants with outflow… More >

Soham Dasgupta, Glen Iannucci, Chad Mao, Martha Clabby, Matthew E. Oster

Congenital Heart Disease, Vol.14, No.5, pp. 868-877, 2019, DOI:10.1111/chd.12835

Abstract Myocarditis has a variable clinical presentation and there is still debate regarding accurate diagnostic criteria. Adding to the controversy surrounding this diagnosis, there is no clear consensus for the treatment or ongoing follow‐up of patients with myocarditis. All of this makes the diagnosis and management of myocarditis a par‐ ticular challenge in the pediatric population. Furthermore, the literature with respect to this topic is dynamic and ever‐changing. In this review article, we aim to review and summarize the common clinical presentations of myocarditis, along with the latest recommendations for diagnostic criteria, treatment, and follow‐up of patients with myocarditis. More >