NARAYANAN NAMPOOTHIRI V. P.1, VIGNESH SUNDARARAJAN1, PALLAVI DAN1, G. DEVANAND VENKATASUBBU2,*, SAHABUDEEN SHEIK MOHIDEEN1,*
BIOCELL, Vol.45, No.5, pp. 1251-1262, 2021, DOI:10.32604/biocell.2021.015090
Abstract Alzheimer’s disease (AD) is one of the most common forms of dementia. Cognitive dysfunction and memory loss are
the two main clinical symptoms of AD. Drosophila melanogaster models of AD, which are based on overexpression of human
amyloid β (Aβ) or human tau (hTau) protein, have been used to study the mechanism underlying AD and to screen potential
therapeutic compounds. Drugs that are currently available for AD provide only symptomatic relief. Huge unmet medical needs
exists to slow, stop, or reverse the progression of AD. Thymoquinone (TQ) is an active ingredient isolated from Nigella sativa
(NS) and possesses various pharmacological… More >
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