Bassem Toeama¹, Nathan Perlis², Paul Grootendorst¹, William Orovan³, Emmanuel Papadimitropoulos^1,4

Canadian Journal of Urology, Vol.31, No.4, pp. 11963-11970, 2024

Abstract Introduction: Prostate cancer is the third leading cause of death from cancer among Canadian men. High intensity focused ultrasound (HIFU) is a novel approach for primary treatment of localized prostate cancer. Little is known, however, about its costs. We aimed to collect the direct costs and health-related quality of life (HRQoL) data of HIFU in primary treatment of localized low and intermediate risk prostate cancer in Ontario.
Materials and methods: We collected direct costs and HRQoL data of 20 patients with localized low or intermediate risk prostate cancer who received whole gland HIFU at a privately owned… More >

Jutarat Tanasansuttiporn¹, Maliwan Oofuvong^1,*, Wirat Wasinwong¹, Voravit Chittithavorn², Pongsanae Duangpakdee², Jirayut Jarutach³, Qistina Yunuswangsa¹

Congenital Heart Disease, Vol.17, No.3, pp. 245-267, 2022, DOI:10.32604/chd.2022.021778 - 03 May 2022

Abstract Background: Studies on predictors of health-related quality of life (HRQOL) in pediatric patients with cyanotic heart disease who are waiting for the next stage and those who have undergone total repair are scarce. Therefore, we aimed to identify such predictors in children who received the modified Blalock–Taussig shunt (MBTS) and those who underwent total repair. Methods: In this historical cohort and concurrent follow-up study, data of children who underwent MBTS at the age of 0–3 years between January 2005 and December 2016 at a super-tertiary care hospital in Southern Thailand were obtained. Children who were alive… More > Graphic Abstract

Lianne M. Geerdink^1,2,*, Malindi van der Mheen^3,4, Gideon J. du Marchie Sarvaas⁵, Irene M. Kuipers⁶, Stefan Frerich⁷, Henriëtte ter Heide², Willem A. Helbing⁸, Zina Feijzic¹, Christian Schroer⁹, Chris L. de Korte¹⁰, Livia Kapusta^1,11, Chris M. Verhaak¹², Elisabeth M. W. J. Utens^3,4

Congenital Heart Disease, Vol.15, No.6, pp. 457-472, 2020, DOI:10.32604/CHD.2020.012994 - 02 November 2020

Abstract Background: Due to the improved survival rates of children and adolescents with congenital heart disease (CHD), more attention is now being directed towards their health-related quality of life (HRQoL), emotional and behavioral problems. Ebstein anomaly (EA) is a rare CHD with a broad clinical spectrum. The aim of the current study is to evaluate self- and proxy-reported HRQoL and emotional and behavioral problems in children and adolescents with EA. Methods: In this cross-sectional, multicenter study, we included EA patients (aged 8–17 years), who underwent routine clinical assessments in Dutch university hospitals between May 2017 and March… More >

Angeles Fuertes-Moure¹, Michael Meyer^2,3, Anna-Luisa Häcker^2,3, Barbara Reiner^2,3, Leon Brudy³, Sonia Pértega-Diaz⁴, Renate Oberhoffer^2,3, Peter Ewert², Jan Müller^2,3,*

Congenital Heart Disease, Vol.15, No.4, pp. 217-227, 2020, DOI:10.32604/CHD.2020.011771 - 07 September 2020

Abstract Objective: Health-related quality of life (HRQoL) has become an important outcome measure for patients with congenital heart disease (CHD). The aim of this study was to evaluate the natural course of HRQoL from longitudinal assessment in children with CHD. Patients and Methods: From July 2014 to February 2020 this longitudinal study recruited 317 children with CHD (113 girls, 35.6%) aged 6 to 18 years (11.6 ± 2.9 years). HRQoL was assessed with the generic, self-reported and age-adapted KINDL^® questionnaire. During a mean follow-up period of 2.2 ± 1.3 years, 195 patients had one HRQoL reassessment, 70 two,… More >

Mazen Alsinnawi¹, Jennifer Cullen^2,3,4, Lauren M. Hurwitz^2,3, Katherine E. Levie^2,3, John F. Burns¹, Inger L. Rosner^2,5, Timothy C. Brand^2,6, Sean Stroup^2,7, Joseph R. Sterbis^2,8, Kevin Rice^2,5, Galen Conti^2,3, Christopher R. Porter^1,2

Canadian Journal of Urology, Vol.26, No.4, pp. 9809-9820, 2019

Abstract Introduction: To assess the impact of primary and secondary therapies for high- and intermediate-risk prostate cancer on health-related quality of life (HRQoL).
Materials and methods: A prospective study was initiated in 2007 at Center for Prostate Disease Research Multicenter National Database sites. Longitudinal patterns in HRQoL from baseline (pre-treatment) to 5 years post-diagnosis were examined for patients with high- and intermediate-risk prostate cancer, treated by radical prostatectomy (RP) or external beam radiation therapy (EBRT). Change in HRQoL was modeled using linear regression models fit with generalized estimating equations. The probability of maintaining HRQoL was compared between patients… More >

Salvatore Siracusano¹, Tommaso Silvestri², Silvia Bassi¹, Antonio Benito Porcaro¹, Maria Angela Cerruto¹, Renato Talamini³, Walter Artibani¹

Canadian Journal of Urology, Vol.25, No.5, pp. 9480-9485, 2018

Abstract Introduction: To evaluate health-related quality of life (HRQoL) in patients with non-muscle invasive bladder cancer (NMIBC) during the induction phase of intravesical instillations with BCG or MMC.
Materials and methods: HRQoL was measured by two questionnaires from EORTC (QLQ-C30 and QLQ-BLS24), stratifying results by gender, age, and therapy at the start of the therapy (T0), at the last instillation (T1), and at 3 months after T1 (T2). The persistence of QoL-related side effects after 3 months from the end of the induction cycle was evaluated.
Results: We enrolled 108 naïve patients, and 103 patients self-completed the questionnaires. Treatment… More >

Astrida Kaugars¹, Clarissa Shields², Cheryl Brosig³

Congenital Heart Disease, Vol.13, No.1, pp. 72-78, 2018, DOI:10.1111/chd.12547

Abstract Objective: The study examined parent stress and health-related quality of life (HRQOL) among families of children with congenital heart disease (CHD) referred for psychological services.
Methods: Parents of 54 children (85% boys) aged 3 to 13 (M_age = 7.48, SD = 2.38) completed measures to assess parenting stress (Parenting Stress Index – Short Form; Pediatric Inventory for Parents) and the PedsQL Family Impact Module. Medical information was retrieved from medical record review.
Results: Half of parents of children with single ventricle anatomy had clinically significant levels of parenting stress. Parents of children with single ventricle anatomy reported more More >

Alvaro Ramirez¹, Paul Perrotte¹, Luc Valiquette¹, Francois Benard¹, Mike McCormack¹, Fred Saad¹, Caroline Fournier¹, Shahrokh Shariat², Pierre I. Karakiewicz¹

Canadian Journal of Urology, Vol.12, No.1, pp. 2537-2542, 2005

Abstract Objectives: We explored the specific impact of urinary diversion type on HRQOL in men after cystectomy for bladder cancer. Our intent was to provide a basis for the development of a diversion-specific instrument.
Methods: We invited 13 ileal conduit and 12 orthotopic urinary diversion (neo-bladder) male patients to several open-ended interviews. We explored HRQOL domains that may have been affected by cystectomy and urinary diversion, and that could then be used to form a basis for a diversion-specific HRQOL measure.
Results: The average age of neo-bladder patients was 59 versus 65 years for ileal conduit patients. We identified More >