Clarissa M. Gurbani¹, Vincent Khor², Jeffrey J. Leow¹, Melissa H.W. Tay³, Yew-Lam Chong¹

Canadian Journal of Urology, Vol.27, No.3, pp. 10270-10272, 2020

Abstract Wunderlich syndrome (WS) is a rare triad of flank pain, flank mass and hypovolemic shock and is classically attributed to angiomyolipomata or neoplasms. Treatment is guided by clinical severity: conservative, selective arterial embolization, or nephrectomy. We report an atypical case of a 69-year old man with a pre-existing 9 cm left renal tumor who developed WS secondary to anticoagulation and simple cyst rupture from his contralateral kidney, complicated by abdominal compartment syndrome with hemodynamic instability despite inotropic support and robust resuscitation. Early recognition and source control via radical nephrectomy were essential in securing a positive More >

Ali. E. Dabiri^1,2,*, Matthew Martin³, Ghassan S. Kassab¹

Molecular & Cellular Biomechanics, Vol.17, No.1, pp. 25-31, 2020, DOI:10.32604/mcb.2019.07310

Abstract The world-wide impact of traumatic injury and associated hemorrhage on human health and well-being is significant. Methods to manage bleeding from sites within the torso, referred to as non-compressible torso hemorrhage (NCTH), remain largely limited to the use of conventional operative techniques. The overall mortality rate of patients with NCTH is approximately 50%. Studies from the wars in Afghanistan and Iraq have suggested that up to 80% of potentially survivable patients die as a result of uncontrolled exsanguinating hemorrhage. The commercially available resuscitative endovascular balloon occlusion of the aorta (REBOA) is a percutaneous device… More >

Humberto Vigil¹, Sender Herschorn¹, Ron Kodama¹, Jon Barrett²

Canadian Journal of Urology, Vol.26, No.2, pp. 9736-9739, 2019

Abstract The incidence of placenta accreta spectrum is on the rise. The most serious entity within this spectrum is percreta: extension beyond the uterus. The bladder is most commonly involved in these cases and is especially relevant for the urologist. Important sequelae include hemorrhage, massive transfusion, maternal mortality and urinary tract injury. Approaching this disorder as well as associated urinary tract involvement in a standardized and multi-disciplinary fashion significantly improves outcomes and reduces morbidity. Herein, we present a case of complete placenta percreta involving the bladder that was successfully managed with minimal obstetrical and genitourinary morbidity. More >

Muyi Guo¹, Yan Cai¹, Zhiyong Li^1,2,*

Molecular & Cellular Biomechanics, Vol.16, Suppl.1, pp. 49-49, 2019, DOI:10.32604/mcb.2019.05727

Abstract Observational studies have identified angiogenesis from the adventitial vasa vasorum and intraplaque hemorrhage (IPH) as critical factors in atherosclerotic plaque progression and destabilization. Here we propose a mathematical model incorporating intraplaque neovascularization and hemodynamic calculation for the quantitative evaluation of atherosclerotic plaque hemorrhage. An angiogenic microvasculature based on histology of a patient’s carotid plaque is generated by two-dimensional nine-point model of endothelial cell migration. Three key cells (endothelial cells, smooth muscle cells and macrophages) and three key chemicals (vascular endothelial growth factors, extracellular matrix and matrix metalloproteinase) are involved in the intraplaque angiogenesis model, and… More >

Dany N. Hanna, Jason A. Levy, Jonah S. Marshall

Canadian Journal of Urology, Vol.24, No.4, pp. 8934-8936, 2017

Abstract Gross hematuria is a common occurrence in adults. The differential diagnosis is extensive, including: malignancy, trauma, infammation of the urinary tract, and stones. While, urinary tract amyloidosis represents only a small percentage of causative gross hematuria, it is concerning because of its superfcial resemblance to malignant processes. We report the case of an 82-year-old male with concurrent primary amyloidosis of the kidney, ureter and bladder in the setting of acute hemorrhage. Histopathological examination of several biopsied samples confrmed our diagnosis. A nephroureterectomy with bladder cuff was successfully performed without complication along with watchful waiting for More >

Jyoti D. Chouhan¹, Hanson H. Zhao², Brian Magee³, Brian K. McNeil¹

Canadian Journal of Urology, Vol.23, No.3, pp. 8324-8328, 2016

Abstract Retroperitoneal hemorrhage and an associated hematoma are uncommon but potentially serious complications following ureteroscopy with laser lithotripsy. However, no reports of serious bleeding complications have been published regarding ureteroscopy without laser lithotripsy in the management of stone disease. We report of such a case here and then review the current literature in order to discuss the incidence, risk factors, and management of such events. More >

Ali-Reza Sharif-Afshar¹, Tom Feng¹, Steven Koopman¹, Christopher Nguyen², Quanlin Li³, Eugene Shkolyar¹, Rola Saouaf², Hyung L. Kim¹

Canadian Journal of Urology, Vol.22, No.2, pp. 7698-7702, 2015

Abstract Introduction: Hemorrhage induced by prostate biopsy can interfere with the interpretation of prostate magnetic resonance imaging (MRI).
Materials and methods: We reviewed 101 patients who had prostate multiparametric MRI (MP-MRI) and radical prostatectomy.
Results: On MRI obtained within 4 weeks following the biopsy, hemorrhage was seen in 26/36 (72.2%) patients. Patients having a MRI between 4-6 weeks of the biopsy had hemorrhage in 8/14 (57.1%) cases. After 6 weeks, hemorrhage was less common but still present in 24/46 (52%) patients. There were five patients who had prostate MRI prior to biopsy and served as a control… More >

Andrew J. Davidiuk, David D. Thiel

Canadian Journal of Urology, Vol.22, No.6, pp. 8105-8107, 2015

Abstract Spontaneous retroperitoneal hematoma (SRH) is a rare, potentially lethal entity that can arise from a variety of etiologies. We present a case of SRH secondary to hemorrhage from the right inferior adrenal artery in a 22-year-old woman. The patient presented to the emergency room with significant right flank pain, and computed tomography (CT) demonstrated a large, right-sided retroperitoneal hematoma with no identifiable etiology. Renal angiography revealed active extravasation from the right inferior adrenal artery. The patient was definitively treated with endovascular coiling of the ruptured artery, and long-term follow-up demonstrated resolution of the retroperitoneal hematoma. More >

Anthony T. Corcoran¹, Ryan P. Smith², Ronald M. Benoit¹

Canadian Journal of Urology, Vol.16, No.3, pp. 4682-4683, 2009

Abstract Prostate brachytherapy is a minimally invasive option in treating prostate cancer, usually with little risk of surgical morbidity. This reports a case of signifi cant bleeding associated with the procedure of prostate brachytherapy. More >

Bilal Chughtai¹, David Samadi², Khurshid A. Guru³, Zelik Frischer⁴, Jamil Rehman⁴

Canadian Journal of Urology, Vol.16, No.4, pp. 4760-4761, 2009

Abstract We report a case of primary granulocytic sarcoma (GS) of the left adrenal gland, with no evidence of hematologic involvement. To our knowledge, this is the fi rst case of granulocytic sarcoma of the adrenal gland. More >