FABIANA ROCHA ARAÚJO¹, BRUNO MACHADO BERTASSOLI², ISABELLA CRISTINA SOUZA FÉLIX¹, DOUGLAS MARINHO ABREU¹, NATáLIA MELO OCARINO¹, AMANDA MARIA SENA REIS³, JUNEO FREITAS SILVA⁴, ROGéRIA SERAKIDES^1,*

BIOCELL, Vol.47, No.2, pp. 423-430, 2023, DOI:10.32604/biocell.2023.023689

Abstract To evaluate the characteristics and synthesis activity of osteoblasts extracted from the calvaria of offspring of rats exposed to maternal hyperthyroidism. Twelve adult Wistar rats were divided into two groups, one control and one treated with daily administration of L-thyroxine by an orogastric tube (50 µg/animal/day) during pregnancy. Three days after delivery and confirmation of the mothers’ hyperthyroidism, the offspring were euthanized for the extraction of osteoblasts from the calvaria. At 7, 14, and 21 days, proliferation activity was assessed using MTT assay, while alkaline phosphatase (ALP) activity was assessed by the BCIP/NBT method. At 21 days, the total area… More >

S. J. K. Jagadeesh Kumar¹, P. Parthasarathi², Mehedi Masud³, Jehad F. Al-Amri⁴, Mohamed Abouhawwash^5,6,*

Intelligent Automation & Soft Computing, Vol.35, No.3, pp. 2909-2924, 2023, DOI:10.32604/iasc.2023.030335

Abstract The main task of thyroid hormones is controlling the metabolism rate of humans, the development of neurons, and the significant growth of reproductive activities. In medical science, thyroid disorder will lead to creating thyroiditis and thyroid cancer. The two main thyroid disorders are hyperthyroidism and hypothyroidism. Many research works focus on the prediction of thyroid disorder. To improve the accuracy in the classification of thyroid disorder this paper proposes optimization-based feature selection by using differential evolution with the Butterfly optimization algorithm (DE-BOA). For the classifier fuzzy C-means algorithm (FCM) is used. The proposed DEBOA-FCM is evaluated with parametric metric measures… More >