Hong Liu1,#,*, Luyao Ma1,#, Jinghang Li1,#, Bingqi Sun2, Siqiang Zheng3, Yongfeng Shao1,*
Congenital Heart Disease, Vol.16, No.5, pp. 443-455, 2021, DOI:10.32604/CHD.2021.015588
Abstract Background: This study evaluated differential inflammatory response to cardiopulmonary bypass reoxygenation in
tetralogy of Fallot repair. Methods: We performed a retrospective study at a cardiovascular center from 2012 to
2018, including 500 patients aged 1 week–18 years who received complete repair of tetralogy of Fallot. Patients were
grouped according to tertiles of preoperative RVOT gradient on echocardiography into mild, moderate, and severe
stenosis. We measured the highest perfusate oxygenation (PpO2) during aortic occlusion as independent variable.
Primary outcome was systemic inflammatory response syndrome (SIRS) within 7 days postoperatively or the time of
death or discharge. Results: Overall, rate of SIRS… More >
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