Satoshi Ii1,*, Keisuke Ito1, Naoya Takakusaki1, Naoya Sakamoto1
Molecular & Cellular Biomechanics, Vol.16, Suppl.2, pp. 49-49, 2019, DOI:10.32604/mcb.2019.07378
Abstract Cells adhere to a substrate and generate traction forces in focal adhesions that enable them to apprehend extracellular mechanical properties [1]. Current concerns are focused on mechanisms how the mechanical balances hold in the cell and affect the cell behavior, and therefore non-invasive measurement techniques for the cell traction forces are required. The cell traction force microscopy (TFM) generalized by Dembo and Wang [2] is an attractive approach to non-invasively estimate cell traction force fields, in which an inverse problem is solved using a mechanical model of the substrate and displacement fields from fluorescent images of immersed beads in the… More >
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