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    A Dynamical Modeling to Study the Adaptive Immune System and the Influence of Antibodiesin the Immune Memory

    Alexandre de Castro1,2, Carlos Frederico Fronza2, Domingos Alves2,3

    CMES-Computer Modeling in Engineering & Sciences, Vol.45, No.1, pp. 83-96, 2009, DOI:10.3970/cmes.2009.045.083

    Abstract Immunological systems have been an abundant inspiration to contemporary computer scientists. Problem solving strategies, stemming from known immune system phenomena, have been successfully applied to chall enging problems of modern computing. Simulation systems and mathematical modeling are also beginning use to answer more complex immunological questions as immune memory process and duration of vaccines, where the regulation mechanisms are not still known sufficiently (Lundegaard, Lund, Kesmir, Brunak, Nielsen, 2007). In this article we studiedin machinaa approach to simulate the process of antigenic mutation and its implications for the process of memory. Our results have suggested More >

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