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    REVIEW

    The Interface of Cancer, Their Microenvironment and Nanotechnology

    Natalia Roque1,#, Diana Matias2,#, Joana Balça-Silva3, Valéria Pereira Ferrer4, Luciana Santos Pessoa1, Tania Cristina Leite de Sampaio e Spohr1,5,*

    Oncologie, Vol.24, No.3, pp. 371-411, 2022, DOI:10.32604/oncologie.2022.024035

    Abstract Cancer is one of the deadliest diseases with a cure far from being found. Despite the extraordinary advances in the therapy approaches, only a few patients respond to treatments. The tumor microenvironment (TME) plays a crucial role in cancer progression by contributing to the chemoresistance. Thus, emerging efforts are being made in nanotechnology research focusing on nanoparticles’ potential role and their application in immune system modulation. Moreover, the omics have contributed to bioengineering and nanotechnology development by elucidating the mechanisms of cancer and specific biomarkers that could be used as new therapeutic targets. Furthermore, the non-coding microRNA as a target… More >

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