Or Bercovich1, Tal Tirosh-Wagner2, Lior Goldberg1, Amir Vardi3, David Mishali4, Gideon Paret1,#, Yael Nevo-Caspi1,*,#
Congenital Heart Disease, Vol.15, No.4, pp. 239-249, 2020, DOI:10.32604/CHD.2020.011576
Abstract Objective: To test the hypothesis that circulating miRNAs-146a, -146b,
-155, and -21 reflect the inflammatory state of children following heart surgery,
and that they may, therefore, correlate with postoperative parameters. We aimed
to quantify miRNAs in blood samples from pediatric patients before and 6, 12,
and 24 hours after surgery and to evaluate correlations between the miRNA levels
and the postoperative course. Setting: PICU. Patients: Forty-two pediatric
patients with CHD who underwent cardiac surgery at Safra Children’s Hospital
between 2012–2016. Interventions: none. Outcome Measures: The primary outcomes were the postoperative cardiac complications and the secondary outcomes
were the length of… More >
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