Fuzhou Tang1, Jin Chen1, Shichao Zhang1, Zuquan Hu1, Lina Liu1, Long Li1, Yan Ouyang1, Zhu Zeng1,*
Molecular & Cellular Biomechanics, Vol.16, Suppl.2, pp. 40-41, 2019, DOI:10.32604/mcb.2019.07082
Abstract As potent antigen presenting cells, dendritic cells (DCs) are utilized to deliver the signals essential for the initiation of immune responses. The motility of DCs is crucial for migration of immature DCs (imDCs) in peripheral tissue and the interaction between mature DCs (mDCs) and naïve T cells in the secondary lymph node. From biomechanical viewpoint, the deformability of cells is necessary for their motility. Deformation of cells can be divided into active deformation (e.g. chemotaxis) and passive deformation (e.g. migration under shear stress of blood flow). However, there is no detailed study on the deformability of DCs including imDCs and… More >
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