Shipra Gupta1, Ankit Sakhuja2, Eric McGrath1, Basim Asmar1
Congenital Heart Disease, Vol.12, No.2, pp. 196-201, 2017, DOI:10.1111/chd.12425
Abstract Background: We studied the incidence, trend, underlying conditions, microbiology, and outcomes
of infective endocarditis (IE) in children during 11 years using Nationwide Inpatient Sample (NIS)
database. This is the largest all-payer inpatient care database in the United States containing data
for more than 8 million hospital stays from over 1000 hospitals.
Methods: NIS data from 2000 to 2010 of primary discharge diagnosis of IE in children aged ≤19
years old were studied. Children with underlying congenital heart defects and acquired heart conditions were identified. Microbiological causative agents were recorded. Linear regression was
used to assess trend of incidence over time.
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