Qi Li1,2, Ningli Wang3, Zhicheng Liu1,2, Lin Li1,2, Zhicheng Liu1,2, Wenjia Wang1,2, Xiaoxue Long1,2, Hongfang Song1,2,*
Molecular & Cellular Biomechanics, Vol.17, No.3, pp. 119-137, 2020, DOI:10.32604/mcb.2020.09529
Abstract Aim: To investigate the relationship between glaucoma and intraocular
pressure (IOP), intracranial pressure (ICP), trans-laminar cribrosa pressure difference (TLCPD), and the newly proposed fractional pressure reserve (FPR). Methods: Ten articles were analyzed by meta-analysis, and subgroup analysis of three
factors was conducted. Results: The patients with normal tension glaucoma
(NTG) and open-angle glaucoma (OAG) have higher TLCPD and lower ICP than
healthy subjects, with obvious heterogeneity. The greater heterogeneity may arise
from different ICP measurements and from different countries or regions. FPR
performs better than TLCPD in some ways. Conclusion: Both FPR and TLCPD
can be used as indicators of… More >
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