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  • Open Access


    Inverse Estimation of 3-D Traction Stress Field of Adhered Cell based on Optimal Control Technique using Image Intensities

    Satoshi Ii1,*, Keisuke Ito1, Naoya Takakusaki1, Naoya Sakamoto1

    Molecular & Cellular Biomechanics, Vol.16, Suppl.2, pp. 49-49, 2019, DOI:10.32604/mcb.2019.07378

    Abstract Cells adhere to a substrate and generate traction forces in focal adhesions that enable them to apprehend extracellular mechanical properties [1]. Current concerns are focused on mechanisms how the mechanical balances hold in the cell and affect the cell behavior, and therefore non-invasive measurement techniques for the cell traction forces are required. The cell traction force microscopy (TFM) generalized by Dembo and Wang [2] is an attractive approach to non-invasively estimate cell traction force fields, in which an inverse problem is solved using a mechanical model of the substrate and displacement fields from fluorescent images of immersed beads in the… More >

  • Open Access


    Inverse Estimation of Moisture Diffusivity by Utilizing Temperature Response of a Drying Body

    G. Kanevce1, L. Kanevce2, V. Mitrevski3, G. Dulikravich4

    The International Conference on Computational & Experimental Engineering and Sciences, Vol.8, No.1, pp. 1-6, 2008, DOI:10.3970/icces.2008.008.001

    Abstract This paper deals with the application of inverse concepts in drying. The objective of the paper is estimation of the moisture diffusivity of a drying body by using only temperature measurements. Potato and apple slices have been chosen as representative drying bodies with significant shrinkage effects. A mathematical model of the drying process of shrinking bodies has been applied. The Levenberg-Marquardt method and a hybrid optimization method of minimization of the least-squares norm were used to solve the present parameter estimation problem. More >

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