Yun Peng¹, Guoan Li^1,*

Molecular & Cellular Biomechanics, Vol.16, Suppl.2, pp. 128-129, 2019, DOI:10.32604/mcb.2019.07392

Abstract This article has no abstract. More >

Zhongzheng Wang^1,2, Fei Tian³, Shaobai Wang³, Songtao Ai², Tsung-Yuan Tsai^1,*

Molecular & Cellular Biomechanics, Vol.16, Suppl.2, pp. 116-117, 2019, DOI:10.32604/mcb.2019.07690

Abstract This article has no abstract. More >

G. Papaioannou¹, G. Nianios¹, C. Mitroyiannis¹, S.Tashman², K.H. Yang²

The International Conference on Computational & Experimental Engineering and Sciences, Vol.8, No.1, pp. 7-12, 2008, DOI:10.3970/icces.2008.008.007

Abstract Little is known about in vivo menisci loads and displacements in the knee during strenuous activities. We have developed a method that combines biplane high-speed dynamic radiography (DRSA) and a subject-specific finite element model for studying in vivo meniscal behavior. In a very controlled uniaxial compression loading condition, removing of the pressure sensor from the model can result in relatively large errors in contact and cartilage stress that are not reflected in the change of meniscal displacement. More >

Y. Bei¹, B.J. Fregly¹, W.G. Sawyer¹, S.A. Banks^1,2, N.H. Kim¹

CMES-Computer Modeling in Engineering & Sciences, Vol.6, No.2, pp. 145-152, 2004, DOI:10.3970/cmes.2004.006.145

Abstract Mild wear of ultra-high molecular weight polyethylene tibial inserts continues to affect the longevity of total knee replacements (TKRs). Using static finite element and elasticity analyses, previous studies have hypothesized that polyethylene wear can be reduced by using a thicker tibial insert to decrease contact pressures. To date, no study has taken this hypothesis to the next step by performing dynamic analyses under in vivo functional conditions to quantify the relationship between contact pressures, insert thickness, and mild wear. This study utilizes multibody dynamic simulations incorporating elastic contact to perform such analyses. \textit {In vivo} fluoroscopic gait data from two… More >

Wangping Duan^∗, Lei Wei^†, Juntao Zhang^∗, Yongzhuang Hao^∗, Chunjiang Li^∗, Hao Li^∗, Qi Li^∗, Quanyou Zhang^‡, Weiyi Chen^‡, Xiaochun Wei^∗,§

Molecular & Cellular Biomechanics, Vol.8, No.4, pp. 253-274, 2011, DOI:10.3970/mcb.2011.008.253

Abstract The cytoskeleton network is believed to play an important role in the biomechanical properties of the chondrocyte. Ours and other laboratories have demonstrated that chondrocytes exhibit a viscoelastic solid creep behavior in vitro and that viscoelastic properties decrease in osteoarthritic chondrocytes. In this study, we aimed to understand whether the alteration of viscoelastic properties is associated with changes in cytoskeleton components of ageing chondrocytes from rabbit knee articular cartilage. Three age groups were used for this study: young (2-months-old, N=23), adult (8-months-old, N=23), and old (31-months-old, N=23) rabbit groups. Cartilage structure and proteoglycan and type II collagen content were determined… More >

P.C. Chen^∗,†, C.W. Colwell^†, D.D. D’Lima^†,‡

Molecular & Cellular Biomechanics, Vol.8, No.2, pp. 135-148, 2011, DOI:10.3970/mcb.2011.008.135

Abstract A nonlinear viscoelastic finite element model of ultra-high molecular weight polyethylene (UHMWPE) was developed in this study. Eight cylindrical specimens were machined from ram extruded UHMWPE bar stock (GUR 1020) and tested under constant compression at 7% strain for 100 sec. The stress strain data during the initial ramp up to 7% strain was utilized to model the "instantaneous" stress-strain response using a Mooney-Rivlin material model. The viscoelastic behavior was modeled using the time-dependent relaxation in stress seen after the initial maximum stress was achieved using a stored energy formulation. A cylindrical model of similar dimensions was created using a… More >

D.D. D’Lima^*, P.C. Chen^†, O. Kessler^‡, H.R. Hoenecke^*, C.W. Colwell Jr.^∗§

Molecular & Cellular Biomechanics, Vol.8, No.2, pp. 123-134, 2011, DOI:10.3970/mcb.2011.008.123

Abstract The menisci are important biomechanical components of the knee. We developed and validated a finite element model of meniscal replacement to assess the effect of surgical fixation technique on contact behavior and knee stability. The geometry of femoral and tibial articular cartilage and menisci was segmented from magnetic resonance images of a normal cadaver knee using MIMICS (Materialise, Leuven, Belgium). A finite element mesh was generated using HyperWorks (Altair Inc, Santa Ana, CA). A finite element solver (Abaqus v6.9, Simulia, Providence, RI) was used to compute contact area and stresses under axial loading and to assess stability (reaction force generated… More >