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    ARTICLE

    Improving the Antibacterial Property of Chitosan Hydrogel Wound Dressing with Licorice Polysaccharide

    Haiwei Ren1, Li Wang1, Hui Bao1, Yunya Xia1, Dada Xu1, Weijie Zhang1,*, Zhiye Wang2

    Journal of Renewable Materials, Vol.8, No.10, pp. 1343-1355, 2020, DOI:10.32604/jrm.2020.010903

    Abstract A series of hydrogels with different ratios of chitosan and licorice polysaccharide (LP) were prepared by crosslinking to different concentrations of genipin (gp). They were characterized by FTIR (Fourier transform infrared spectroscopy), SEM (Scanning electron microscope), swelling ratio, rheological measurements, degradation with time, cytotoxicity, and antibacterial efficacy. Results show that the hydrogels have porous structures. With an increase in LP content, the swelling rate grows in the early stage of immersion in buffer and drops later. The swelling ratio ranged from 986% to 1677%, and stiffness varied from 777 Pa to 1792 Pa. The addition of LP reduced the mechanical… More >

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