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  • Open Access

    ARTICLE

    An Efficient Allocation for Lung Transplantation Using Ant Colony Optimization

    Lina M. K. Al-Ebbini*

    Intelligent Automation & Soft Computing, Vol.35, No.2, pp. 1971-1985, 2023, DOI:10.32604/iasc.2023.030100

    Abstract A relationship between lung transplant success and many features of recipients’/donors has long been studied. However, modeling a robust model of a potential impact on organ transplant success has proved challenging. In this study, a hybrid feature selection model was developed based on ant colony optimization (ACO) and k-nearest neighbor (kNN) classifier to investigate the relationship between the most defining features of recipients/donors and lung transplant success using data from the United Network of Organ Sharing (UNOS). The proposed ACO-kNN approach explores the features space to identify the representative attributes and classify patients’ functional status (i.e., quality of life) after… More >

  • Open Access

    ARTICLE

    Benefit of prophylactic bronchodilator with β2 adrenergic agonist in ischemia-reperfusion-induced lung injury

    CHEN-LIANG TSAI1, YU-HUEI LIN2, CHIH-YING CHANGCHIEN3, CHIH-FENG CHIAN1,#,*, CHI-HUEI CHIANG4,#,*

    BIOCELL, Vol.45, No.5, pp. 1201-1211, 2021, DOI:10.32604/biocell.2021.014279

    Abstract Primary lung graft dysfunction could significantly attribute to ischemia-reperfusion lung injury (IRLI) during transplantation surgery. β2-adrenergic agonists were one of the bronchodilators that had been well-established in the management of asthma and chronic obstructive pulmonary disease (COPD) with anti-inflammatory potency. By applying the model of isolated rat lung, we evaluated the efficacy of short-acting β2-agonist inhalation to ameliorate ischemia-reperfusion damage. The experiment protocol was 180 min of global ischemia and then reperfusion for 60 min. In the β2-agonist inhalation group, aerosolized albuterol was administrated prior ischemia procedure. Increased weight ratios of wet to dry lung and microvascular permeability were characterized… More >

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