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  • Open Access

    ARTICLE

    Synthesis of MoS2/Fe3O4 composites for the detection of liver cancer biomarker alpha-fetoprotein

    C. B. Cuia,b, G. C. Yangb, Z. Zhanga,, X. J. Wangc,

    Chalcogenide Letters, Vol.22, No.6, pp. 507-520, 2025, DOI:10.15251/CL.2025.226.507

    Abstract This research introduces an innovative aptasensor for detecting alpha-fetoprotein with exceptional sensitivity and specificity, employing a novel MoS2/Fe3O4 composite fabricated through an advanced in-situ growth methodology. The composite exhibited a hierarchical flower-like structure with uniformly distributed Fe3O4 nanoparticles, confirmed by SEM, XRD, and Raman spectroscopy. The MoS2/Fe3O4 composite demonstrated a 66% increase in surface area (7.16 m²/g) compared to pristine MoS2, enhancing aptamer immobilization and electron transfer efficiency. Electrochemical characterization revealed a significant increase in interfacial resistance upon AFP binding, with a detection limit of 0.3 pg/mL and a dual linear range of 0.001–0.1 ng/mL and 0.1–100 More >

  • Open Access

    ARTICLE

    Performance Analysis of Magnetic Nanoparticles during Targeted Drug Delivery: Application of OHAM

    Muhammad Zafar1,#,*, Muhammad Saif Ullah1,#, Tareq Manzoor2, Muddassir Ali3, Kashif Nazar4, Shaukat Iqbal5, Habib Ullah Manzoor6, Rizwan Haider1, Woo Young Kim7,*

    CMES-Computer Modeling in Engineering & Sciences, Vol.130, No.2, pp. 723-749, 2022, DOI:10.32604/cmes.2022.017257 - 13 December 2021

    Abstract In recent years, the emergence of nanotechnology experienced incredible development in the field of medical sciences. During the past decade, investigating the characteristics of nanoparticles during fluid flow has been one of the intriguing issues. Nanoparticle distribution and uniformity have emerged as substantial criteria in both medical and engineering applications. Adverse effects of chemotherapy on healthy tissues are known to be a significant concern during cancer therapy. A novel treatment method of magnetic drug targeting (MDT) has emerged as a promising topical cancer treatment along with some attractive advantages of improving efficacy, fewer side effects,… More >

  • Open Access

    ARTICLE

    Impacts of Heat Flux Distribution, Sloping Magnetic Field and Magnetic Nanoparticles on the Natural Convective Flow Contained in a Square Cavity

    Latifa M. Al-Balushi, M. M. Rahman*

    FDMP-Fluid Dynamics & Materials Processing, Vol.16, No.3, pp. 441-463, 2020, DOI:10.32604/fdmp.2020.08551 - 25 May 2020

    Abstract In the present paper, the effect of the heat flux distribution on the natural convective flow inside a square cavity in the presence of a sloping magnetic field and magnetic nanoparticles is explored numerically. The nondimensional governing equations are solved in the framework of a finite element method implemented using the Galerkin approach. The role played by numerous model parameters in influencing the emerging thermal and concentration fields is examined; among them are: the location of the heat source and its lengthH*, the magnitude of the thermal Rayleigh number, the nanoparticles shape and volume fraction, and… More >

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