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    Review : Role of mast cells in gastrointestinal mucosal defense

    Alicia B. Penissi*, María I. Rudolph**, Ramón S. Piezzi*

    BIOCELL, Vol.27, No.2, pp. 163-172, 2003, DOI:10.32604/biocell.2003.27.163

    Abstract The purpose of this review, based on studies from our laboratory as well as from others, is to summarize salient features of mast cell immunobiology and to describe their associations with gastrointestinal mucosal defense. Gastrointestinal mast cells are involved in many pathologic effects, such as food hypersensitivity. On the other hand, they also play a protective role in defense against parasitic and microbial infections. Thus, they have both positive and negative effects, but presently the mechanisms that control the balance of these various effects are poorly known. It has been suggested that stabilization of mast cells may be a key… More >

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