Edo Bedzra^1,*, Eli Contorno², Herra Javed², Amna Qasim³, James St. Louis⁴, Taufiek Konrad Rajab²

Congenital Heart Disease, Vol.19, No.6, pp. 541-562, 2024, DOI:10.32604/chd.2025.059788 - 27 January 2025

Abstract Since the first identification of Tetralogy of Fallot in 1671, consisting of a combination of anatomical defects including biventricular origin of the aorta, maligned ventricular septal defect, overriding aorta, and narrowing or atresia of the pulmonary outflow tract. The first successful operation consisted of a shunt between the left subclavian artery and pulmonary artery. Following this palliative procedure, complete repair is performed once the patient reaches indicative criteria. Since the first attempts at surgical palliation and repair, techniques and outcomes have improved drastically. Definitive repair of Tetralogy of Fallot consists of a multi-patch closure of More >

Brandon Van Asseldonk, Jack Barkin, Dean S. Elterman

Canadian Journal of Urology, Vol.22, Suppl.5, pp. 7-17, 2015

Abstract instruction: Introduction: Benign prostatic hyperplasia (BPH) is a common disease that affects men as they age. Historically the treatment has been primarily surgical in nature, but over the past 25 years significant advances in medical therapy have been made, sparing some men from interventional procedures.
instruction: Materials and methods: This article highlights the current state-of-the-art with respect to medical therapy for lower urinary tract symptoms secondary to BPH (BPH-LUTS) including a review of landmark studies and recent areas of research in the field.
instruction: Results: Alpha blockers are considered first line when treating BPH-LUTS in men with… More >

Sabeer Rehsia, Bobby Shayegan

Canadian Journal of Urology, Vol.19, Suppl.5, pp. 28-35, 2012

Abstract Prostate cancer remains a common cancer diagnosis and cause of cancer-related death in men. Despite it’s high prevalence, screening for prostate cancer for early detection remains controversial. This article outlines evidence from contemporary prostate cancer screening clinical trials and presents an overview of therapeutic options across the spectrum of prostate-cancer states. More >

Sidney B. Radomski¹, Jack Barkin²

Canadian Journal of Urology, Vol.19, Suppl.5, pp. 2-9, 2012

Abstract Overactive bladder (OAB) with or without urinary incontinence is a common condition in both men and women. OAB has a signifcant impact on quality of life for most patients. In most cases, sophisticated testing is not required for a primary care physician to diagnose OAB and start treating a patient. Management of OAB requires behavioral modifcation and, if necessary, pharmacotherapy may be added. If a patient does not respond to treatment initiated by a primary care physician, then he or she should be referred to a specialist in OAB to undergo further investigations and treatments. More >

Gerald H. Jordan

Canadian Journal of Urology, Vol.14, Suppl.6, pp. 69-74, 2007

Abstract Peyronie's disease is a scarring phenomenon of the penis causing various deformities; initially pain with erection, and in most patients is associated with some element of erectile dysfunction. Studies of the natural history of the disease show that Peyronie's disease is a self-limited condition. In its stable and quiescent phase, patients have stable deformity, and in some cases that deformity then requires surgery.
For the most part, pharmacologic therapy is confined to the immature or active phase of the disease. Pharmacotherapy is aimed at trying to adjust or interfere with the scarring process, so that the… More >

Jeffrey W. Nix, Culley C. Carson

Canadian Journal of Urology, Vol.14, Suppl.6, pp. 53-57, 2007

Abstract Benign prostatic hyperplasia (BPH) is a common condition of the aging male. The bladder outlet obstruction caused by this condition occurs despite variations in prostate size. Symptoms of BPH include the irritative and obstructive voiding symptoms termed lower urinary tract symptoms (LUTS). While transurethral surgery has long been the gold standard for treatment of LUTS, medical treatment has emerged as the first line of treatment for those men who fail expectant or watchful waiting treatment. Medical options include: alpha blockers, 5α-reductase inhibitors and newly identified PDE 5 inhibitors, drugs for erectile dysfunction that have a… More >