Chun Yang1,2, Dalin Tang2,3 Satya Atluri4
CMES-Computer Modeling in Engineering & Sciences, Vol.57, No.1, pp. 51-76, 2010, DOI:10.3970/cmes.2010.057.051
Abstract Cardiovascular disease (CVD) is becoming the number one cause of death worldwide. Atherosclerotic plaque rupture and progression are closely related to most severe cardiovascular syndromes such as heart attack and stroke. Mechanisms governing plaque rupture and progression are not well understood. A computational procedure based on three-dimensional meshless generalized finite difference (MGFD) method and serial magnetic resonance imaging (MRI) data was introduced to quantify patient-specific carotid atherosclerotic plaque growth functions and simulate plaque progression. Participating patients were scanned three times (T1, T2, and T3, at intervals of about 18 months) to obtain plaque progression data. Vessel wall thickness (WT) changes… More >
Login
Register
