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  • Open Access

    ARTICLE

    Biomechanical Study of Different Scaffold Designs for Reconstructing a Traumatic Distal Femur Defect Using Patient-Specific Computational Modeling

    Hsien-Tsung Lu1,2, Ching-Chi Hsu3,*, Qi-Quan Jian3, Wei-Ting Chen4

    CMES-Computer Modeling in Engineering & Sciences, Vol.142, No.2, pp. 1883-1898, 2025, DOI:10.32604/cmes.2025.057675 - 27 January 2025

    Abstract Reconstruction of a traumatic distal femur defect remains a therapeutic challenge. Bone defect implants have been proposed to substitute the bone defect, and their biomechanical performances can be analyzed via a numerical approach. However, the material assumptions for past computational human femur simulations were mainly homogeneous. Thus, this study aimed to design and analyze scaffolds for reconstructing the distal femur defect using a patient-specific finite element modeling technique. A three-dimensional finite element model of the human femur with accurate geometry and material distribution was developed using the finite element method and material mapping technique. An… More > Graphic Abstract

    Biomechanical Study of Different Scaffold Designs for Reconstructing a Traumatic Distal Femur Defect Using Patient-Specific Computational Modeling

  • Open Access

    ARTICLE

    Deep Reinforcement Learning for Multi-Phase Microstructure Design

    Jiongzhi Yang, Srivatsa Harish, Candy Li, Hengduo Zhao, Brittney Antous, Pinar Acar*

    CMC-Computers, Materials & Continua, Vol.68, No.1, pp. 1285-1302, 2021, DOI:10.32604/cmc.2021.016829 - 22 March 2021

    Abstract This paper presents a de-novo computational design method driven by deep reinforcement learning to achieve reliable predictions and optimum properties for periodic microstructures. With recent developments in 3-D printing, microstructures can have complex geometries and material phases fabricated to achieve targeted mechanical performance. These material property enhancements are promising in improving the mechanical, thermal, and dynamic performance in multiple engineering systems, ranging from energy harvesting applications to spacecraft components. The study investigates a novel and efficient computational framework that integrates deep reinforcement learning algorithms into finite element-based material simulations to quantitatively model and design 3-D More >

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