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  • Open Access

    ARTICLE

    Cytoplasmic Motion Induced by Cytoskeleton Stretching and Its Effect on Cell Mechanics

    T. Zhang*

    Molecular & Cellular Biomechanics, Vol.8, No.3, pp. 169-194, 2011, DOI:10.3970/mcb.2011.008.169

    Abstract Cytoplasmic motion assumed as a steady state laminar flow induced by cytoskeleton stretching in a cell is determined and its effect on the mechanical behavior of the cell under externally applied forces is demonstrated. Non-Newtonian fluid is assumed for the multiphase cytoplasmic fluid and the analytical velocity field around the macromolecular chain is obtained by solving the reduced nonlinear momentum equation using homotopy technique. The entropy generation by the fluid internal friction is calculated and incorporated into the entropic elasticity based 8-chain constitutive relations. Numerical examples showed strengthening behavior of cells in response to externally More >

  • Open Access

    ARTICLE

    Thermocapillary and Natural Convection in Double Layer Systems of Herschel-Bulkley and Newtonian Fluids, Exact Solutions

    O.M.Lavrenteva, Yu. Holenbergand A.Nir1

    FDMP-Fluid Dynamics & Materials Processing, Vol.6, No.1, pp. 41-74, 2010, DOI:10.3970/fdmp.2010.006.041

    Abstract A variety of exact analytical solutions describing natural and thermocapillary convection in a horizontal double layer system consisting of Newtonian and Herschel-Bulkley fluids subjected to longitudinal temperature and concentration gradients is constructed. The lower boundary of the system is a solid wall with no-slip, while the upper ones if either a solid wall or a free surface. It was demonstrated that, depending on the governing parameters of the system, viscoplastic layer is entirely yielded or unyielded, or it can be yielded partially, exhibiting up to 5 flowing and quasi-solid layers. The dependence of the flow More >

  • Open Access

    ARTICLE

    Solution of Phase Change Problems by Collocation with Local Pressure Correction

    G. Kosec1, B. Šarler2

    CMES-Computer Modeling in Engineering & Sciences, Vol.47, No.2, pp. 191-216, 2009, DOI:10.3970/cmes.2009.047.191

    Abstract This paper explores an application of a novel mesh-free Local Radial Basis Function Collocation Method (LRBFCM) [Sarler and Vertnik (2006)] in solution of coupled heat transfer and fluid flow problems with solid-liquid phase change. The melting/freezing of a pure substance is solved in primitive variables on a fixed grid with convection suppression, proportional to the amount of the solid fraction. The involved temperature, velocity and pressure fields are represented on overlapping sub-domains through collocation by using multiquadrics Radial Basis Functions (RBF). The involved first and second derivatives of the fields are calculated from the respective… More >

  • Open Access

    ARTICLE

    The Effect of the Reynolds Number on Lateral Migration of Nonneutrally-Buoyant Spherical Particles in Poiseuille Flow

    S.-C. Hsiao1, M.S. Ingber2

    CMC-Computers, Materials & Continua, Vol.1, No.1, pp. 51-58, 2004, DOI:10.3970/cmc.2004.001.051

    Abstract The lateral migration of nonneutrally-buoyant spherical particles in Poiseuille flow is investigated numerically using the boundary element method. In particular, the steady, Navier-Stokes equations are solved using a classical domain integration method treating the nonlinear terms as pseudo-body forces. The numerical results for the lateral migration velocity are compared with experimental data. The numerical results indicate that the lateral migration velocity does not scale linearly with the Reynolds number. The methodology is extended to include non-Newtonian power-law fluids. The migration velocity is significantly affected for particles suspended in this class of fluids and can actually More >

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