Xin Hu1,2,#, Fangyu Jing3,#, Qingjun Wang1,4, Linyang Shi1, Yunfeng Cao4,5, Zhitu Zhu1,4,*
Oncologie, Vol.23, No.2, pp. 203-217, 2021, DOI:10.32604/Oncologie.2021.016155
Abstract It is noteworthy that colon cancer is the fourth place in new cases and the fifth in mortalities according to global cancer statistics 2018. Tumorigenesis displays specific correlation with metabolic alterations. A variety of metabolites, including ornithine (Orn), are related to colon cancer according to sources of disease metabolic information retrieval in human metabolome database. The metabolic regulation of Orn pathway is a key link in the survival of cancer cells. In this study, the plasma Orn levels in colon cancer patients and healthy participants were measured by liquid chromatography tandem mass spectrometry, and the metabolic disturbances of Orn in… More >
Login
Register
