Hua Yang*
Oncologie, Vol.24, No.4, pp. 835-863, 2022, DOI:10.32604/oncologie.2022.026447
Abstract Background: Epithelial ovarian cancer (EOC) is the deadliest malignancy among the gynecologic tumors, and ovarian serous cystadenocarcinoma (OV) is the dominant histological type. Ferroptosis is a novel iron-dependent, programmed form of cell death, and agents that trigger ferroptosis may constitute potential anti-cancer therapies.
Materials and Methods: We herein extracted the genes that participate in the process of ferroptosis from the online
FerrDb database to create a ferroptosis-related genome (FRG), and then comprehensively analyzed the relationship
between the mRNA expression of each gene and the clinicopathologic features of The Cancer Genome Atlas
(TCGA)-OV cohort. Results: We found that most of the… More >
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