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  • Open Access

    ARTICLE

    Reactive Oxygen Species-Mediated Cezanne Inactivation by Oxidation of its Catalytic Cysteine Residue in Hepatocellular Carcinoma

    Zhongyuan Yin*, Lin Yang, Feng Wu, Jinshuo Fan, Juanjuan Xu, Yang Jin, Guanghai Yang§

    Oncology Research, Vol.27, No.9, pp. 1069-1077, 2019, DOI:10.3727/096504019X15566157027506

    Abstract Cysteine oxidation occurs at the active site of deubiquitinases (DUBs) during many biologic signaling cascades. Here we report that hepatocellular carcinoma cells (HCCs) generated higher levels of endogenous reactive oxygen species (ROS). This elevated ROS production was inhibited by NADPH oxidase inhibitor diphenylene iodonium (DPI) and mitochondria electron chain inhibitor rotenone in HCC cells. Moreover, we found that H2O2 could activate NF- B-dependent inflammatory effect through increased induction of matrix metalloproteinase 2 (MMP2), MMP9, and intercellular adhesion molecule 1 (ICAM1) expression levels. In addition, we found that H2O2 could prolong NF- B activation by suppressing the negative regulatory functions of… More >

  • Open Access

    ARTICLE

    Divicine induces endothelial cells injury and its potential mechanism

    LONG SU#, ZHEXUAN LIN#, HUI LI, HONGJUN LUO, WENHONG LUO*

    BIOCELL, Vol.46, No.7, pp. 1725-1732, 2022, DOI:10.32604/biocell.2022.018508

    Abstract Divicine is an active pyrimidine aglycone, generated from vicine by the enzyme β-glucosidase upon ingestion of fava beans. In this study, we investigated the effect of divicine on cultured human umbilical vein endothelial cells (HUVECs) and explored the potential mechanisms. Incubation HUVECs with 18.5–85.1 μM divicine resulted in a concentration and time dependent decrease of cell viability, followed by decrease of cellular reduced glutathione, as well as increase of reactive oxygen species (ROS), malondialdehyde (MDA), and labile iron pool. Transmission electron microscopy confirmed that the divicine treated HUVECs’ mitochondria had shrunk. Importantly, the administration of desferrioxamine, an iron chelator, to… More >

  • Open Access

    ARTICLE

    Experimental Research on Mercury Catalytic Oxidation over Ce Modified SCR Catalyst

    Yadi Qin, Qiyu Weng, Yuqun Zhuo*

    Energy Engineering, Vol.119, No.1, pp. 35-47, 2022, DOI:10.32604/EE.2022.015477

    Abstract In order to improve the ability of SCR catalyst to catalyze the oxidation of gaseous elemental mercury, a series of novel Ce modified SCR (Selection Catalytic Reduction, V2O5–WO3/TiO2) catalysts were prepared via two-step ultrasonic impregnation method. The performance of Ce/SCR catalysts on Hg0 oxidation and NO reduction as well as the catalytic mechanism on Hg0 oxidation was also studied. The XRD, BET measurements and XPS were used to characterize the catalysts. The results showed that the pore volume and pore size of catalyst was reduced by Ce doping, and the specific surface area decreased with the increase of Ce content… More >

  • Open Access

    ARTICLE

    Oxidative effects of glyphosate on the lipophobic intracellular environment in the microalgae Chlorella vulgaris

    JUAN MANUEL OSTERA1,2, SUSANA PUNTARULO1,2, GABRIELA MALANGA1,2,*

    BIOCELL, Vol.46, No.3, pp. 795-802, 2022, DOI:10.32604/biocell.2022.017294

    Abstract

    The studied hypothesis is that the herbicide glyphosate (GLY) can affect the oxidative balance in the hydrophobic intracellular medium in non-target Chlorella vulgaris cells. Analytical GLY and RoundUp (RUP) supplementation, affected the growth profile. A significant 42% decrease in the cellular biomass in stationary (St) phase was observed in cultures supplemented with either 5 µM of GLY or RUP, as compared to control cultures. The treatment with 0.3 µM of GLY generated non-significant effects on the oxidation rate of 2’, 7’ dichlorofluorescein diacetate (DCFH-DA), neither in exponential (Exp) nor in St phase of development, as compared to control cultures. However,… More >

  • Open Access

    ARTICLE

    A Study on the Relationship between Anodic Oxidation and the Thermal Load on the Aluminum Alloy Piston of a Gasoline Engine

    Huali Guo*, Yi Liang, Zhilong Zhang, Yuanhua Chen

    FDMP-Fluid Dynamics & Materials Processing, Vol.18, No.1, pp. 57-70, 2022, DOI:10.32604/fdmp.2022.017989

    Abstract In order to analyze the influence of the anodizing process on the thermal load of an aluminum alloy piston, dedicated temperature tests have been carried out using the Hardness Plug method and the results for the anodized piston have been compared with those obtained separately for an original aluminum piston. In addition, numerical simulations have been conducted to analyze the temperature field and thermal stress distribution. Simulations and experiments show that the maximum temperature of the anodized piston is 16.36% and 5.4% smaller than that of the original piston under the condition of maximum torque and maximum power, respectively. The… More >

  • Open Access

    REVIEW

    Application of Fe-Based Amorphous Alloy in Industrial Wastewater Treatment: A Review

    Liefei Pei, Xiangyun Zhang, Zizhou Yuan*

    Journal of Renewable Materials, Vol.10, No.4, pp. 969-991, 2022, DOI:10.32604/jrm.2022.017617

    Abstract Amorphous alloy (MGs) is a solid alloy with disordered atomic accumulation obtained by ultra-rapid solidification of alloy melt. The atom deviates from the equilibrium position and is in metastable state. Up to now, a large number of MGs have been applied to the treatment of dye and heavy metal contaminated wastewater and ideal experimental results have been obtained. However, there is no literature to systematically summarize the chemical reaction and degradation mechanism in the process of degradation. On the basis of reviewing the classification, application, and synthesis of MGs, this paper introduces in detail the chemical reactions such as decolorization,… More >

  • Open Access

    ARTICLE

    Changes in Growth, Photosynthetic Pigments, Cell Viability, Lipid Peroxidation and Antioxidant Defense System in Two Varieties of Chickpea (Cicer arietinum L.) Subjected to Salinity Stress

    Zeenat Mushtaq1, Shahla Faizan1, Basit Gulzar2, Humira Mushtaq3, Sayyada Bushra1, Alisha Hussain1, Khalid Rehman Hakeem4,*

    Phyton-International Journal of Experimental Botany, Vol.91, No.1, pp. 149-168, 2022, DOI:10.32604/phyton.2022.016231

    Abstract Salinity is one of the most severe abiotic stresses for crop production. The present study investigates the salinity-induced modulation in growth indicators, morphology and movement of stomata, photosynthetic pigments, activity of carbonic anhydrase as well as nitrate reductase, and antioxidant systems in two varieties of chickpea (Pusa-BG5023, and Pusa-BGD72). On 20th day of sowing, plants were treated with varying levels of NaCl (0, 50, 100, 150 and 200 mM) followed by sampling on 45 days of sowing. Recorded observations on both the varieties reveal that salt stress leads to a significant decline in growth, dry biomass, leaf area, photosynthetic pigments,… More >

  • Open Access

    ARTICLE

    An α-Fe2O3/Circulating Fluidized Bed Fly Ash Based Geopolymer Composite Anode for Electrocatalytic Degradation of Indigo Carmine Dye Wastewater

    Jiaqian Lei, Yaojun Zhang*, Panyang He

    Journal of Renewable Materials, Vol.9, No.12, pp. 2277-2289, 2021, DOI:10.32604/jrm.2021.015824

    Abstract Geopolymers have been developed to various catalysts due to their advantages. However, low conductivity restricts their application in the electrocatalysis field. In this study, an α-Fe2O3/circulating fluidized bed fly ash based geopolymer (CFAG) composite anode was fabricated using a facile dip-coating method by loading α-Fe2O3 in the matrix of CFAG. The effects of α-Fe2O3 content on the composition, surface morphology and electrochemical performance of α-Fe2O3/CFAG composite anode were investigated. The X-ray diffraction (XRD) and scanning electron microscope (SEM) results demonstrated that α-Fe2O3 was successfully inlaid with the surface of amorphous CFAG matrix. The electrochemical measurements indicated that α-Fe2O3/CFAG composite anode… More > Graphic Abstract

    An α-Fe<sub>2</sub>O<sub>3</sub>/Circulating Fluidized Bed Fly Ash Based Geopolymer Composite Anode for Electrocatalytic Degradation of Indigo Carmine Dye Wastewater

  • Open Access

    ARTICLE

    Optimum Calculation of Coal Pillars in Inclined Weathered Oxidation Zone

    Yingbo Zhang1, Shi Chen1,2,*

    Energy Engineering, Vol.118, No.3, pp. 707-714, 2021, DOI:10.32604/EE.2021.013888

    Abstract In the mining process of coal mine, waterproof coal pillars should be set between the weathered oxidation zone and the first mining face. In order to determine the reasonable upper limit of the first mining face of Hongyi Coal Mine, the waterproof coal pillar needs to be wide enough to resist the lateral hydrostatic pressure of the oxidation zone, and to ensure that the top plate aquifer does not run through the water guide crack zone, while also liberating as much stagnant coal as possible. In this paper, the first coal mine face’s waterproof coal pillar was calculated using conventional… More >

  • Open Access

    ARTICLE

    Preparation of Cellulose Nanofibrils by Multi-Site Regioselective Oxidation

    Liying Song1, Xixiang Pei2, Rui Li1, Haitao Chen1,*, Xiaozheng Sun1,*

    Journal of Renewable Materials, Vol.8, No.10, pp. 1269-1282, 2020, DOI:10.32604/jrm.2020.010923

    Abstract Cellulose nanofibrils (CNFs) are promising sustainable materials that can be applied to nanocomposites, as well as medical and life-sciences devices. However, methods for the preparation of these important materials are energy intensive because heating and mechanical disintegration are required to produce cellulose fibers below 100 nm in size. In this study, CNFs were prepared through the multi-site regioselective oxidation of cellulose with 2,2,6,6-tetramethylpiperidine-1-oxyl (TEMPO) and periodate at room temperature (20–25°C), without any mechanical-disintegration treatment. Transmission electron microscopy (TEM) revealed that the CNFs had the average widths of 14.1, 55.4, and 81.9 nm for three different treatments. Fourier-transform infrared spectroscopy revealed… More >

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