Caojin Zhang^1,#, Haibo Hu^2,#, Gangcheng Zhang^3,#, Qiguang Wang⁴, Xiaobin Chen⁵, Yingzhang Cheng⁶, Qunshan Shen⁷, Jie Yuan⁸, Wenqi Zhang⁹, Yuanshi Li¹⁰, Xuan Zheng³, Xiangbin Pan^2,*, Professional Committee of National Quality Management and Control Center for Structural Heart Diseases, Professional Committee of Structural Heart Diseases of the National Cardiovascular Disease Expert Committee

Congenital Heart Disease, Vol.20, No.4, pp. 403-420, 2025, DOI:10.32604/chd.2025.071050 - 18 September 2025

Abstract Compared with traditional nickel-titanium alloy patent foramen ovale occluders, which are widely used in clinical practice, biodegradable patent foramen ovale occluders have obvious differences in material characteristics, interventional operation mode and postoperative management strategy. This article gives expert consensus on the selection of clinical indications and standardized operating procedures, so as to standardize the clinical application of biodegradable patent foramen ovale occluders. More >

Su Ye¹, Luxi Guan¹, Dong Luo¹, Fengwen Zhang¹, Jianhua Lv¹, Qizong Xie², Qiao Huang², Haiming Wu², Haibo Hu^1,*, Xiangbing Pan^1,*

Congenital Heart Disease, Vol.20, No.2, pp. 181-193, 2025, DOI:10.32604/chd.2025.063297 - 30 April 2025

Abstract Objectives: This study aimed to evaluate the feasibility, safety, and efficacy of a novel transcatheter suture closure system (HaloStitch^®) for patent foramen ovale (PFO) closure in a swine model. Methods: Thirteen swine underwent experimental PFO model creation. All animals received implantation of the transcatheter suture closure system to evaluate procedural success. Comprehensive follow-up over six months included serial ultrasound imaging, histopathological analysis, and gross anatomical examination of cardiac specimens. Results: Successful HaloStitch^® device implantation was achieved in 11 of 13 swine. Gross anatomical examination confirmed secure positioning of all sutures in the atrial septum, with no redundancy or… More >

Xingbang Li^1,#, Xuan Zheng^2,#, Bowen Jin¹, Yunyan Li¹, Yongyu Shao¹, Xiaoxian Deng¹, Dingyang Li¹, Shanshan Li¹, Hongmei Zhou¹, Jie Zhang³, Xianya Zhang⁴, Qunshan Shen¹, Gangcheng Zhang^2,*

Congenital Heart Disease, Vol.18, No.4, pp. 489-489, 2023, DOI:10.32604/chd.2023.031413 - 15 September 2023

Abstract This article has no abstract. More >

Xingbang Li^1,#, Xuan Zheng^2,#, Bowen Jin¹, Yunyan Li¹, Yongyu Shao¹, Xiaoxian Deng¹, Dingyang Li¹, Shanshan Li¹, Hongmei Zhou¹, Jie Zhang³, Xianya Zhang⁴, Qunshan Shen¹, Gangcheng Zhang^2,*

Congenital Heart Disease, Vol.18, No.3, pp. 373-385, 2023, DOI:10.32604/chd.2023.028979 - 09 June 2023

Abstract Background: Transcatheter closure of patent foramen ovale (PFO) has been widely accepted as a highly effective way to treat high-risk PFO-related diseases. However, traditional non-degradable occluders made of metal alloys will permanently exist in the body, resulting in thrombosis, valve damage, hemolysis, arrhythmia, or other complications. The biodegradable PFO occluder developed by Shanghai Mallow Medical Instrument Co., Ltd., China can be fully absorbed and degrade into nontoxic ingredients, reducing postoperative complications. Objectives: To study the safety and efficacy of biodegradable PFO occluders in treating PFO. Methods: This single-center clinical trial collected 30 patients treated with a More > Graphic Abstract

Biagio Castaldi^1,*, Giulio Cabrelle¹, Massimo Padalino², Vladimiro Vida², Ornella Milanesi¹, Giovanni Di Salvo¹

Congenital Heart Disease, Vol.15, No.5, pp. 347-360, 2020, DOI:10.32604/CHD.2020.012750 - 23 September 2020

Abstract Background: Trans-catheter closure has become the treatment of choice for patent foramen ovale (PFO) and ostium secundum atrial septal defects (ASD). A wide variety of devices are commercially available, however, concerns have been raised about the risk of cardiac erosion associated with stiff/rigid devices. The GORE® CARDIOFORM Septal Occluder (GSO) is a double-disc, soft and conformable device with no reported incidence of cardiac erosions. However, wire frame fracture (WFF) have been reported. Aim: To assess the incidence and clinical significance of WFF after GSO implantation in paediatric patients. Methods: Seventy-seven consecutive patients were enrolled. Periprocedural and follow-up… More >