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  • Open Access

    REVIEW

    Role of Platelet Derivatives and Their Therapeutic Potential in Wound Healing

    Sanggu Kim1, Seongmo Yang1, Soochong Kim1,2,*

    BIOCELL, Vol.49, No.12, pp. 2335-2364, 2025, DOI:10.32604/biocell.2025.072418 - 24 December 2025

    Abstract Regenerative medicine has attracted increasing attention across diverse organs, including the skin, musculoskeletal tissues, eye, and nervous system, where structural repair is limited. Among these, skin wound care is particularly urgent and challenging because diabetic ulcers, pressure injuries, and severe burns often resist standard dressings, debridement, and revascularization, resulting in infection, amputation, and high costs. Platelet-rich plasma (PRP) has gained value because platelets release coordinated growth factors and cytokines (e.g., platelet-derived growth factor, transforming growth factor-β, vascular endothelial growth factor, epidermal growth factor, fibroblast growth factor, and insulin-like growth factor-1) that modulate hemostasis, inflammation, angiogenesis,… More >

  • Open Access

    REVIEW

    It’s in the blood: plasma as a source for biochemical identification and biological characterization of novel leukocyte chemoattractants

    Jo Van Damme1, Stijn Van Damme2, Soffe Struyf1, Ghislain Opdenakker3

    European Cytokine Network, Vol.36, No.1, pp. 6-14, 2025, DOI:10.1684/ecn.2025.0501 - 05 January 2026

    Abstract Since their discovery, chemotactic cytokines or chemokines have been intensively studied for about half a century. Chemokines originate from tissue cells, leukocytes, blood platelets and plasma. Here, we review a number of seminal findings on plasma chemokines within an historical and international context. These aspects include how induction and purification protocols led to the discovery of a new family of mediators, named chemokines, on the basis of protein sequencing; how molecular cloning techniques facilitated discoveries of additional family members on the basis of conserved protein structures; how blood plasma and platelets were used as a More >

  • Open Access

    ARTICLE

    Improving the Environmental Friendliness of Glued Structures Made of Thermal Wood by Preliminary Low-Temperature Plasma Treatment

    Ksenia Saerova*, Ruslan Safin

    Journal of Renewable Materials, Vol.13, No.9, pp. 1829-1840, 2025, DOI:10.32604/jrm.2025.02025-0076 - 22 September 2025

    Abstract This article presents research focused on developing and scientifically substantiating a technology for producing environmentally friendly glued structures from wood treated through a two-stage process. The methodology involves preliminary thermal modification followed by high-frequency low-temperature plasma treatment. Thermal modification enhances performance characteristics such as resistance to rot, lowers hygroscopicity, and increases dimensional stability. However, it can diminish the adhesive properties of wood, complicating the bonding process. To address this challenge, the study introduces high-frequency low-temperature plasma treatment, which activates the wood surface, improving wettability and adhesion while minimizing glue consumption. Experimental results indicate that plasma More >

  • Open Access

    ARTICLE

    Hypoxia-induced exosomal lncRNA-PVT1 as a biomarker and mediator of EMT in hepatocellular carcinoma

    LIBO LIANG1, XINYI WANG2,3,4, YUPING ZENG2,3,4, HAO CHEN2,3,4, WEN ZHOU1, HONGYING MU2,3,4, GA LIAO5,6,*

    Oncology Research, Vol.33, No.6, pp. 1405-1421, 2025, DOI:10.32604/or.2024.056708 - 29 May 2025

    Abstract Objectives: Exosomal long noncoding RNAs (lncRNAs) might facilitate epithelial–mesenchymal transition (EMT) in liver cancer after transarterial chemoembolization (TACE), thereby enhancing tumor cell invasiveness and migration. This study investigated the prognostic role of plasma exosomal long noncoding RNA-plasmacytoma variant translocation 1 (lncRNA-PVT1) in TACE treated hepatocellular carcinoma (HCC). Methods: Plasma exosomal lncRNA-PVT1 was evaluated via qPCR before and after TACE. Hepatoma cell behavior was investigated in different HCC cell lines. A lncRNA-PVT1 plasmid was synthesized and overexpressed, and si-lncRNA PVT1 was transfected into poorly invasive cells to reveal its influence on cell characteristics. The lncRNA-PVT1–FoxM1 interaction… More > Graphic Abstract

    Hypoxia-induced exosomal lncRNA-PVT1 as a biomarker and mediator of EMT in hepatocellular carcinoma

  • Open Access

    ARTICLE

    Research on the Hydrophobic Performance of Bamboo Surface Treated via Coordinated Plasma and PDMS Solution Treatments

    Zihan Ma1,2, Yan Wu1, Hongyan Wang2,*, Shaofei Yuan2, Jian Zhang2

    Journal of Renewable Materials, Vol.13, No.5, pp. 931-955, 2025, DOI:10.32604/jrm.2025.02024-0040 - 20 May 2025

    Abstract Herein, the surface of Moso bamboo was hydrophobically modified by combining O2/N2 plasma treatments with polydimethylsiloxane (PDMS) solution treatment as the hydrophobic solution. The effects of plasma treatment process (power and time), PDMS solution concentration, and maceration time on the hydrophobic performance of bamboo specimens were studied, and the optimal treatment conditions for improving the hydrophobicity were determined. Scanning electron microscopy (SEM), fourier transform infrared (FTIR), X-ray diffraction (XRD), and X-ray photoelectron spectroscopy (XPS) were used to analyze the surface morphology, chemical structure, and functional groups in the specimens before and after the plasma and PDMS… More > Graphic Abstract

    Research on the Hydrophobic Performance of Bamboo Surface Treated via Coordinated Plasma and PDMS Solution Treatments

  • Open Access

    ARTICLE

    Artificial Neural Networks for Optimizing Alumina Al2O3 Particle and Droplet Behavior in 12kK Ar-H2 Atmospheric Plasma Spraying

    Ridha Djebali1,*, Bernard Pateyron2, Mokhtar Ferhi1, Mohamed Ouerhani3, Karim Khemiri1, Montassar Najari1, M. Ammar Abbassi4, Chohdi Amri5, Ridha Ennetta6, Zied Driss7

    Frontiers in Heat and Mass Transfer, Vol.23, No.2, pp. 441-461, 2025, DOI:10.32604/fhmt.2025.063375 - 25 April 2025

    Abstract This paper investigates the application of Direct Current Atmospheric Plasma Spraying (DC-APS) as a versatile thermal spray technique for the application of coatings with tailored properties to various substrates. The process uses a high-speed, high-temperature plasma jet to melt and propel the feedstock powder particles, making it particularly useful for improving the performance and durability of components in renewable energy systems such as solar cells, wind turbines, and fuel cells. The integration of nanostructured alumina (Al2O3) thin films into multilayer coatings is considered a promising advancement that improves mechanical strength, thermal stability, and environmental resistance. The More >

  • Open Access

    REVIEW

    A review on pathobiology of circulating tumour plasma cells: The sine qua non of poor prognosis in plasma cell neoplasms

    PRATIBHA SUKU1, AISHWARYA DASH1, ARAVIND RADHAKRISHNAN1, PANKAJ MALHOTRA2, MAN UPDESH SINGH SACHDEVA1,*

    Oncology Research, Vol.33, No.5, pp. 1055-1068, 2025, DOI:10.32604/or.2024.055154 - 18 April 2025

    Abstract Circulating plasma cells (CPCs) in patients of plasma cell neoplasm have been an area of intense research in recent decades. Circulating tumor plasma cells (CTPCs) might represent a sub-clone of tumor cells that have exited into peripheral blood as a result of the dynamic interactions between the bone marrow (BM) microenvironment and neoplastic plasma cells. Chemokine receptors like chemokine receptor 4 (CXCR4) and integrins are known to play a role in homing and migration of plasma cells (PCs). The hypoxic microenvironment in the BM niche also contributes to their circulation through various mechanisms. In addition,… More >

  • Open Access

    ARTICLE

    Er3+-doped SiO2-TeO2-ZnO-Na2O thin film fabricated by ultrafast laser plasma doping under different ambient atmospheres

    S. A. Kamila,b,*, G. Josec

    Chalcogenide Letters, Vol.21, No.1, pp. 11-20, 2024, DOI:10.15251/CL.2024.211.11

    Abstract Er3+-ions doped SiO2-ZnO-Na2O thin films were fabricated using ultrafast laser plasma doping (ULPD) techniques under different ambient atmospheres; vacuum, nitrogen, oxygen and argon gas. The thickness of the layer produced depends on the ambient atmosphere during fabrication. The layer fabricated under a vacuum is the thinnest among all of the samples. In addition, the surface layer for the sample fabricated under a vacuum environment seems to be relatively smoother compared with those of the others. XRD patterns show that all samples are in a mixed amorphous-crystalline phase. All the Raman spectra exhibited a similar pattern, except More >

  • Open Access

    PROCEEDINGS

    The Influence of Leading Mode on the Stability of Plasma and Molten Pool in the Laser-MIG Hybrid Welding Process of Invar Alloy

    Qiyu Gao1, Xiaohong Zhan1,*

    The International Conference on Computational & Experimental Engineering and Sciences, Vol.30, No.1, pp. 1-1, 2024, DOI:10.32604/icces.2024.012448

    Abstract Invar alloy is widely used in the field of aeronautical composite die manufacturing because it has a very low coefficient of thermal expansion, which is like that of composite material. The laser-MIG (Metal-Inert Gas) hybrid welding was developed to join 10 mm thick Invar alloy plates using Invar M93 filling wire. High speed camera equipment was used to observe plasma dynamic processes. Three-dimensional finite element models of laser-MIG hybrid welding process were established to solve the flow field of the molten pool by two leading modes. Elaborated on the flow behavior of the molten pool More >

  • Open Access

    PROCEEDINGS

    A Few Key Scientific Advances of MGE

    Xiaodong Xiang1,*

    The International Conference on Computational & Experimental Engineering and Sciences, Vol.29, No.1, pp. 1-1, 2024, DOI:10.32604/icces.2024.012861

    Abstract Material genes could be understood as the relationship between composition (element, valence state, function group, etc.), structure (lattice, molecular weight, defect, etc.), thermodynamic parameters (temperature, time, pressure, etc.) and physical properties, represented as materials phase diagrams [1-3]. I will discuss 1) a recently developed an optical plasma resonance spectrum method to characterize the electrical transport properties; 2)the progress in studying dynamic phase diagrams;3)the progress using advanced neural network algorisms to predict materials key properties. More >

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