Narongsak Yotha1, Qusain Hiader2, Zulqurnain Sabir3, Muhammad Asif Zahoor Raja4, Salem Ben Said5, Qasem Al-Mdallal5, Thongchai Botmart6, Wajaree Weera6,*
CMC-Computers, Materials & Continua, Vol.74, No.2, pp. 2415-2430, 2023, DOI:10.32604/cmc.2023.031352
Abstract This study aims to solve the nonlinear fractional-order mathematical model (FOMM) by using the normal and dysregulated bone remodeling of the myeloma bone disease (MBD). For the more precise performance of the model, fractional-order derivatives have been used to solve the disease model numerically. The FOMM is preliminarily designed to focus on the critical interactions between bone resorption or osteoclasts (OC) and bone formation or osteoblasts (OB). The connections of OC and OB are represented by a nonlinear differential system based on the cellular components, which depict stable fluctuation in the usual bone case and unstable fluctuation through the MBD.… More >
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