Jessica C. Dai¹, Tara N. Morgan¹, Alaina Garbens¹, Samuel Kusin², Hersh Trivedi², Claus G. Roehrborn¹, Jeffrey C. Gahan¹

Canadian Journal of Urology, Vol.29, No.2, pp. 11052-11058, 2022

Abstract Introduction: Anticholinergic or ß-3 agonist use following robotic simple prostatectomy (RASP) is not well described. We describe rates of antispasmodic use following RASP and identify potential predictors of medication use.
Materials and methods: A retrospective review of all RASP patients from 2/2016 - 1/2020 was conducted. Patients with no preoperative International Prostate Symptom Score (IPSS) were excluded. Demographics, clinical data, and postoperative medication use were collected by electronic medical record review. Multivariable logistic regression analysis using a priori variables was performed to identify independent factors associated with antispasmodic use.
Results: A total of 255 patients underwent RASP at… More >

Jutarat Tanasansuttiporn¹, Maliwan Oofuvong^1,*, Wirat Wasinwong¹, Voravit Chittithavorn², Pongsanae Duangpakdee², Jirayut Jarutach³, Qistina Yunuswangsa¹

Congenital Heart Disease, Vol.17, No.3, pp. 245-267, 2022, DOI:10.32604/chd.2022.021778 - 03 May 2022

Abstract Background: Studies on predictors of health-related quality of life (HRQOL) in pediatric patients with cyanotic heart disease who are waiting for the next stage and those who have undergone total repair are scarce. Therefore, we aimed to identify such predictors in children who received the modified Blalock–Taussig shunt (MBTS) and those who underwent total repair. Methods: In this historical cohort and concurrent follow-up study, data of children who underwent MBTS at the age of 0–3 years between January 2005 and December 2016 at a super-tertiary care hospital in Southern Thailand were obtained. Children who were alive… More > Graphic Abstract

Mohamed Saber Hafez^*, Alaa Roushdy, Dina Ezzeldin

Congenital Heart Disease, Vol.17, No.3, pp. 325-333, 2022, DOI:10.32604/chd.2022.019025 - 03 May 2022

Abstract Background: Coarctation of the aorta is a congenital heart disease that sometimes remains clinically silent until adulthood, usually presenting with arterial hypertension. It is well known that after coarctation treatment, many patients remain hypertensive despite successful repair. In this study we approached the predictors and effects of residual hypertension after successful coarctation therapy. Methods: It was a cross sectional observational study involving 50 patients who underwent Coarctation repair/angioplasty in Ain Shams university hospitals. We divided the patients into two groups (hypertensive and normotensive) and we studied their demographic data (e.g., age, gender, age at first repair,… More >

Ankur Choksi¹, Shu Wang¹, Michael Phelan¹, Heather Mannuel², Michael Naslund¹, Mohummad Minhaj Siddiqui¹

Canadian Journal of Urology, Vol.28, No.1, pp. 10547-10555, 2021

Abstract Introduction: Complete pathologic response (pT0) at time of cystectomy after neoadjuvant chemotherapy (NAC) has been associated with significantly improved clinical outcomes. The goal of this study is to examine whether race is a predictor of pT0 response to NAC at time of cystectomy.
Materials and methods: We analyzed the records of patients diagnosed with a non-metastatic (M0) muscle-invasive (cT2+) urothelial cell bladder cancer in the National Cancer Database (NCDB) who underwent a cystectomy from 2006 to 2014. The cohort was stratified by whether the patient received NAC prior to cystectomy. Univariate and multivariate logistic regression models were… More >

Cheryl Raskind-Hood^1,*, Kashaine A. Gray^2,3, Jayne Morgan³, Wendy M. Book^4,*

Congenital Heart Disease, Vol.16, No.4, pp. 333-355, 2021, DOI:10.32604/CHD.2021.014384 - 19 April 2021

Abstract Early intervention to prevent premature mortality is vital for adults with congenital heart defects (CHD). Anatomic complexity and comorbid conditions are thought to contribute to CHD mortality. Since hypertension (HTN) and heart failure (HF) are the comorbid conditions among the most prevalent causes of death in the United States, and commonly accompany CHD, it is crucial to evaluate whether they are reliable predictors of mortality for adults with CHD (ACHD) independent of anatomic CHD complexity. A retrospective cross-sectional analysis of ACHD, aged 18–64, with concomitant HTN and/or HF and at least one health care encounter… More >

Jacob Lucas¹, Ryan Barlotta¹, Matthew Brennan¹, Pak Leung², Amir S. Patel¹, Robert G. Uzzo¹, Jay Simhan¹

Canadian Journal of Urology, Vol.27, No.6, pp. 10456-10460, 2020

Abstract Introduction: Evidence suggests overutilization of procedural intervention for renal traumas. The objective of this study was to assess clinical factors associated with procedural intervention for patients presenting to the emergency department (ED) with isolated renal trauma.
Materials and methods: A United States statewide trauma registry was queried for trauma patients presenting to level I or II trauma centers with isolated renal injuries (Grades I–V) from 2000-2013. Patient demographics, mechanism, American Association for the Surgery of Trauma (AAST) grade, trauma center level designation, presenting ED vital signs, Glasgow Coma Scale (GCS), intubation status, and blood product transfusion were assessed.
… More >

Félix Couture^1,2,*, Stefano Polesello², Côme Tholomier^2,3, Helen Davis Bondarenko², Pierre I. Karakiewicz², Sebastiano Nazzani^4,5, Felix Preisser^5,6, Assaad El-Hakim², Kevin C. Zorn⁷

Canadian Journal of Urology, Vol.26, No.1, pp. 9644-9653, 2019

Abstract Introduction: Neurovascular bundle (NVB) preservation during robot-assisted radical prostatectomy (RARP) directly affects patient functional outcomes. Despite careful surgical planning, many NVB preservation techniques are changed intraoperatively from their preoperative plan. Our objective was to identify risk factors predicting intraoperative change in NVB preservation technique during RARP.
Materials and methods: Prospective data from 578 RARPs performed by a single surgeon between 2010 and 2017 at a tertiary care center. Side-specific NVB preservation technique was planned preoperatively. Surgical techniques were either complete nerve sparing (CNS), or incomplete nerve sparing (INS). Variables included age, tumor grade, prostate volume, number of… More >

Stephen J. Dolgner^1,2,3, Eric V. Krieger^1,3, Jacob Wilkes⁴, Susan L. Bratton⁵, Ravi R. Thiagarajan^6,7, Cindy S. Barrett⁸, Titus Chan^1,2,9

Congenital Heart Disease, Vol.14, No.4, pp. 559-570, 2019, DOI:10.1111/chd.12758

Abstract Objective: Adult congenital heart disease (ACHD) patients who undergo cardiac surgery are at risk for poor outcomes, including extracorporeal membrane oxygenation support (ECMO) and death. Prior studies have demonstrated risk factors for mortality, but have not fully examined risk factors for ECMO or death without ECMO (DWE). We sought to identify risk factors for ECMO and DWE in adults undergoing congenital heart surgery in tertiary care children’s hospitals.
Design: All adults (≥18 years) undergoing congenital heart surgery in the Pediatric Health Information System (PHIS) database between 2003 and 2014 were included. Patients were classified into three groups:… More >

Matthew Lewis¹, William Whang², Angelo Biviano², Kathleen Hickey², Hasan Garan², Marlon Rosenbaum¹

Congenital Heart Disease, Vol.14, No.2, pp. 207-212, 2019, DOI:10.1111/chd.12695

Abstract Background: Catheter ablation is commonly performed to treat atrial arrhythmias in adult congenital heart disease (ACHD). Despite the frequency of ablations in the ACHD population, predictors of recurrence remain poorly defined.
Objective: We sought to determine predictors of arrhythmia recurrence in ACHD patients following catheter ablation for atrial arrhythmias.
Methods: We performed a retrospective study of all catheter ablations for atrial arrhythmias performed in ACHD patients between January 12, 2005 and February 11, 2015 at our institution. Prespecified exposures of interest and time from ablation to recurrence were determined via chart review.
Results: Among 124 patients (mean age: 45… More >

Nachiketh Soodana-Prakash¹, Raymond Balise^1,2, Bruno Nahar¹, Vivek Venkatramani¹, Joseph Palmer¹, Nicola Pavan¹, Taylor A. Johnson¹, Samarpit Rai¹, Ramgopal Satyanarayana¹, Chad Ritch¹, Sanoj Punnen¹, Dipen J. Parekh¹, Mark L. Gonzalgo¹

Canadian Journal of Urology, Vol.25, No.4, pp. 9395-9400, 2018

Abstract Introduction: Minimally invasive nephroureterectomy (MINU) and open nephroureterectomy (ONU) have similar oncological outcomes for treatment of upper tract urothelial carcinoma (UTUC). We investigated perioperative outcomes and predictors of complications associated with MINU and ONU.
Material and methods: Using the National Surgical Quality Improvement Program (NSQIP) database, 912 patients were identified that underwent radical nephroureterectomy for UTUC between 2005 and 2013. Logistic regression and contingency table methods used preoperative covariates to predict rates of major (Clavien-Dindo grade ≥ 3) and 16 common perioperative complications. Additional comparisons between treatment groups were performed using unpaired t-tests, Wilcoxon rank-sum tests, or… More >