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  • Open Access

    ARTICLE

    Comparison of Time-Varying Pattern of Recurrence in Chinese Breast Cancer Patients with Different Molecular Subtypes: A Single-Center Retrospective Study

    Xujie Zhou1,2,3,#, Yuting Sang1,3,#, Jiajian Chen1,3, Miao Mo3,4, Jianjing Hou1,3, Benlong Yang1,3,*, Jiong Wu1,2,3,*

    Oncologie, Vol.24, No.3, pp. 451-469, 2022, DOI:10.32604/oncologie.2022.025226 - 19 September 2022

    Abstract Background: To compare the time-varying recurrence patterns of different molecular subtypes of breast cancer in the contemporary era with those in the past era. Patients and Methods: This retrospective study included 14627 consecutive invasive breast cancer patients who underwent surgery from 2008 to 2016 at Fudan University Shanghai Cancer Center. We defined the period from 2013 to 2016 as the contemporary era and that from 2008 to 2012 as the past era. Five subtypes were defined according to the immunohistochemistry results. Emphasis was made on the changing patterns of recurrence for patients with different molecular subtypes changed… More >

  • Open Access

    ARTICLE

    Maximizing intravesical therapy options: is there an advantage to the administration of perioperative mitomycin C prior to an induction course of BCG?

    Gina M. Badalato, Gregory Hruby, Mani Razmjoo, James M. McKiernan

    Canadian Journal of Urology, Vol.18, No.5, pp. 5890-5895, 2011

    Abstract Introduction: This study aimed to evaluate cancer-specific outcomes among patients who received perioperative mitomycin C (MMC) prior to induction BCG compared to those who received induction BCG alone.
    Materials and methods: Between January 2000 and August 2010, 260 patients were identified who underwent a course of induction BCG with or without concomitant perioperative MMC. Specifically, patients who received 40 mg MMC following transurethral resection of all visible tumors, followed by an induction course of BCG, were compared to a similar cohort receiving induction BCG alone. The primary endpoints were overall survival and recurrence-free survival (RFS).
    Results: A total… More >

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