Yuanxiang Luo^*, Linshu Cai, Nan Zhang

Energy Engineering, Vol.122, No.2, pp. 765-783, 2025, DOI:10.32604/ee.2024.058426 - 31 January 2025

Abstract Large-scale new energy grid connection leads to the weakening of the system frequency regulation capability, and the system frequency stability is facing unprecedented challenges. In order to solve rapid frequency fluctuation caused by new energy units, this paper proposes a new energy power system frequency regulation strategy with multiple units including the doubly-fed pumped storage unit (DFPSU). Firstly, based on the model predictive control (MPC) theory, the state space equations are established by considering the operating characteristics of the units and the dynamic behavior of the system; secondly, the proportional-differential control link is introduced to… More > Graphic Abstract

RENATA DA SILVA CARNEIRO¹, MATEUS HENRIQUE DE ALMEIDA DA COSTA¹, JOSé ZILTON LIMA VERDE SANTOS¹, VALDILéIA TEIXEIRA UCHôA², LUCIANO DA SILVA LOPES³, ANDERSON NOGUEIRA MENDES^1,*

BIOCELL, Vol.49, No.1, pp. 109-125, 2025, DOI:10.32604/biocell.2024.058405 - 24 January 2025

Abstract Neurodegenerative diseases are a major public health challenge, mainly affecting the elderly population and compromising their cognitive, sensory, and motor functions. Currently, available therapies focus on alleviating symptoms and slowing the progression of these conditions, but they do not yet offer a definitive cure. In this scenario, terpenes emerge as promising natural alternatives due to their neuroprotective properties. These compounds can reduce the formation of protein aggregates, neutralize free radicals, and inhibit pro-inflammatory enzymes, which are crucial factors in the development of neurodegenerative diseases. In addition, terpenes also play an important role in the… More >

PIAO YANG¹, MOHSEN SHEYKHHASAN^2,*, REZA HEIDARI³, MOHSEN CHAMANARA^4,5, PAOLA DAMA⁶, AMIRHOSSEIN AHMADIEH-YAZDI⁷, HAMED MANOOCHEHRI⁸, HAMID TANZADEHPANAH⁹, HANIE MAHAKI¹⁰, NASER KALHOR¹¹, ASHKAN DIRBAZIYAN¹², SHARAFALDIN AL-MUSAWI¹³

Oncology Research, Vol.33, No.2, pp. 283-300, 2025, DOI:10.32604/or.2024.052939 - 16 January 2025

Abstract Cancer, a leading cause of global mortality, remains a significant challenge to increasing life expectancy worldwide. Forkhead Box R2 (FOXR2), identified as an oncogene within the FOX gene family, plays a crucial role in developing various endoderm-derived organs. Recent studies have elucidated FOXR2-related pathways and their involvement in both tumor and non-tumor diseases. Dysregulation of FOXR2 has been linked to numerous malignant tumors, spanning the brain, nervous system, thyroid, osteosarcoma, Hodgkin lymphoma, colorectal, liver, pancreatic, lung, breast, ovarian, prostate, female genital tract, endometrial, and uterine cancers. Despite extensive research on FOXR2 dysregulation, its practical applications More >

Shukang Lyu^*, Fei Zeng, Huachun Han, Huiyu Miao, Yi Pan, Xiaodong Yuan

Energy Engineering, Vol.122, No.1, pp. 221-242, 2025, DOI:10.32604/ee.2024.056380 - 27 December 2024

Abstract The high proportion of uncertain distributed power sources and the access to large-scale random electric vehicle (EV) charging resources further aggravate the voltage fluctuation of the distribution network, and the existing research has not deeply explored the EV active-reactive synergistic regulating characteristics, and failed to realize the multi-timescale synergistic control with other regulating means, For this reason, this paper proposes a multilevel linkage coordinated optimization strategy to reduce the voltage deviation of the distribution network. Firstly, a capacitor bank reactive power compensation voltage control model and a distributed photovoltaic (PV) active-reactive power regulation model are… More >

YUEZHOU ZHANG^1,#, ZHAO ZHANG^2,#, JINXIN DONG¹, CHANGAN LIU^1,*

Oncology Research, Vol.33, No.1, pp. 83-102, 2025, DOI:10.32604/or.2024.055866 - 20 December 2024

Abstract Background: Aberrant expression of RNA-binding proteins (RBPs) has been linked to a variety of diseases, including hematological disorders, cardiovascular diseases, and multiple types of cancer. Heterogeneous nuclear ribonucleoprotein C (HNRNPC), a member belonging to the heterogeneous nuclear ribonucleoprotein (hnRNP) family, plays a pivotal role in nucleic acid metabolism. Previous studies have underscored the significance of HNRNPC in tumorigenesis; however, its specific role in malignant tumor progression remains inadequately characterized. Methods: We leveraged publicly available databases, including The Cancer Genome Atlas (TCGA), to explore the potential involvement of HNRNPC across various cancers. Additionally, we performed experimental… More > Graphic Abstract

GENGYUN SUN^1,*, YIPING ZHENG^1,2, JIANFENG CAI², JIE GAO², LIE DONG², XIANGBIN ZHANG², YINGHUI HUANG^2,*

Oncology Research, Vol.33, No.1, pp. 171-184, 2025, DOI:10.32604/or.2024.047626 - 20 December 2024

Abstract Background: Long noncoding RNA, LINC01106 exhibits high expression in lung adenocarcinoma (LUAD) tumor tissues, but its functional role and regulatory mechanism in LUAD cells remain unclear. Methods: LINC01106 expression was analyzed in LUAD tissues and its functional impact on LUAD cells was assessed. LUAD cells were silenced with sh-LINC01106 and injected into nude mice to investigate tumor growth. The downstream transcription factors and molecular mechanism were determined using the Human transcription factor database (TFDB) database and Gene Expression Profiling Interactive Analysis (GEPIA) database. Additionally, the impact of linc01106 on autophagy was analyzed by determining the… More > Graphic Abstract

XUETING HUANG¹, CHAOJIE XU², CHEN LI^3,*, ZHIXIAN PAN^1,*

BIOCELL, Vol.48, No.12, pp. 1805-1813, 2024, DOI:10.32604/biocell.2024.056431 - 30 December 2024

Abstract Background: Hyperuricemia is a metabolic disorder which is characterized by increased serum uric acid levels, which can contribute to serious health issues such as gout, cardiovascular disease, and kidney damage. Epigenetic modifications, for example, DNA methylation, exert a crucial function in gene regulation and have been implicated in various metabolic disorders. The ATP-Binding Cassette Subfamily G Member 2 (ABCG2) gene is involved in uric acid excretion, and its expression can be influenced by methylation of its promoter region. Methods: This study involved the design of three guide RNA (gRNA) sequences targeting specific CpG sites within… More >

Ivan Couée^*

Phyton-International Journal of Experimental Botany, Vol.93, No.11, pp. 2707-2714, 2024, DOI:10.32604/phyton.2024.058101 - 30 November 2024

Abstract The 15-carbon terpenoid abscisic acid (ABA) acts in vascular plants as a versatile hormone playing essential roles in reproductive development, vegetative development and growth, stress-development interactions, and physiological responses to abiotic and biotic stresses. Over the past 60 years, ABA dynamics, regulation, and responses have been progressively characterized: synthesis, transport and translocation, conjugation and deconjugation, metabolism, sensing, signal transduction, and downstream responses. In this context, the discovery of ABA exporters and importers has added novel dimensions to the understanding of ABA regulation. Moreover, since the initial discovery of the adenosine triphosphate-binding cassette (ABC) AtABCG25 exporter… More >

Yue Jiang^1,2,#, Lingyu Liu^1,#, Kangyu Wang^1,2, Mingzhu Zhao^1,2, Ping Chen^1,2, Jun Lei^1,2, Yanfang Wang³, Meiping Zhang^1,2, Yi Wang^1,2,*, Guang Chen^1,*

Phyton-International Journal of Experimental Botany, Vol.93, No.11, pp. 3055-3071, 2024, DOI:10.32604/phyton.2024.056384 - 30 November 2024

Abstract The main active components of ginseng are ginsenosides, which play significant roles in treating cardiovascular diseases, cancer, and providing antioxidant effects. Ginsenosides are primarily synthesized through the mevalonate pathway and the methylerythritol phosphate pathway. Many key enzyme genes involved in this biosynthetic process have been cloned and validated, yet the regulatory functions of transcription factors remain unclear. The C₂H₂-type zinc finger protein family, one of the largest families of transcription factors, is crucial in plant growth and development, response to biotic and abiotic stresses, and regulation of secondary metabolism. This study, based on the ginseng transcriptome More >

Ziran Li¹, Weihao Zhang², Lei Qi^1,*

The International Conference on Computational & Experimental Engineering and Sciences, Vol.30, No.4, pp. 1-1, 2024, DOI:10.32604/icces.2024.013344

Abstract In the future, the wide speed and altitude range aviation engine will have features such as "wide range of high-bypass-ratio adjustment" and "wide range of high-pressure-ratio adjustment". Therefore, its turbine will work in a very wide range of operating conditions, with a large flow regulation range. Under conditions of high-rate flow regulation, existing flow control technologies can significantly reduce turbine efficiency. To support the performance and technical specifications of future engines, their low-pressure turbines need to maintain high operational efficiency within a flow regulation range and power output range that exceed those of current aircraft engines.
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