Angela Silvano^*†1, Giulio Menegazzi^*1, Silvia Peppicelli^*1, Caterina Mancini^*, Alessio Biagioni^*, Alessandro Tubita^*, Ignazia Tusa^*, Jessica Ruzzolini^*, Matteo Lulli^*, Elisabetta Rovida^*, Persio Dello Sbarba^*

Oncology Research, Vol.29, No.1, pp. 33-46, 2021, DOI:10.3727/096504022X16442289212164

Abstract This study was directed to deepen the effects of nutrient shortage on BCR/Ablprotein expression and signaling in chronic myeloid leukemia (CML) cells. The backbone of the study was cell culture in medium lacking glucose, the consumption of which we had previously shown to drive BCR/Ablprotein suppression, and glutamine, the other main nutrient besides glucose. In this context, we focused on the role of lactate, the main by-product of glucose metabolism under conditions of rapid cell growth, in particular as a modulator of the maintenance of CML stem/progenitor cell potential, a crucial determinant of disease course and relapse of disease. The… More >

Andrew D. Spearman¹, Rohit S. Loomba², Michael Danduran¹, Joshua Kovach¹

Congenital Heart Disease, Vol.13, No.3, pp. 369-376, 2018, DOI:10.1111/chd.12577

Abstract Objective: Multiple studies demonstrate the association of intrauterine growth restriction (IUGR) with impaired aerobic fitness in adolescents and adults. To our knowledge, there are no studies including individuals with the history of both IUGR and congenital heart disease (CHD). Thus, we sought to evaluate the impact of IUGR on exercise capacity in adolescents with CHD.
Study Design: We conducted a retrospective chart review of patients <18 years of age who underwent cardiopulmonary exercise testing (CPET) between August 1, 2003 and July 1, 2016. Individuals with birth weight <10th percentile for gestational age were defined as IUGR. Patients with IUGR were… More >

Jae Hyun Kim¹, Tae Hyun Kim^2,3,*

International Journal of Mental Health Promotion, Vol.22, No.1, pp. 1-9, 2020, DOI:10.32604/IJMHP.2020.010995

Abstract This study investigates whether restricted participation in productive activity is associated with cognitive health in Korea. Furthermore, given the enormous socioeconomic disparities between aging and gender differences in employment, we also examine whether these associations vary by gender and age. Data from the Korean Longitudinal Study of Ageing (KLoSA) from 2006 to 2016 was used and 9,942 subjects were included at baseline in 2006. To analyze the association between restricted economic activity due to health condition and cognitive function, generalized estimating equation (GEE) model and chi-square test were used. Of the 9,942 individuals at baseline in 2006, the odds ratio… More >

Jianping Wei¹, Xianyue Su^1,2

CMES-Computer Modeling in Engineering & Sciences, Vol.37, No.1, pp. 65-84, 2008, DOI:10.3970/cmes.2008.037.065

Abstract The steady-state response of the wave propagation in a magneto-electro-elastic square column (MEESC) was studied. Some new characteristics were discovered: the guided waves are classified in the forms of the Quasi-P, Quasi-SV and Quasi-SH waves and ordered by the standing wave number, and the three type guided waves are corresponding to the extension, twist and shear modes of the body vibration; the induced electric and magnetic fields can be aroused by the propagating stress wave. We proposed a self-adjoint method, by which the guided-wave restriction condition was derived. After finding the corresponding orthogonal sets, the analytic dispersion equation was obtained.… More >