Arunn Narasimhan^*, Kaushal Kumar Jha

Frontiers in Heat and Mass Transfer, Vol.2, No.3, pp. 1-8, 2011, DOI:10.5098/hmt.v2.3.3005

Abstract Pan Retinal photocoagulation (PRP), a retinal laser surgical process, is simulated using a three-dimensional bio-heat transfer numerical model. Spots of two different type of array, square array of 3 × 3 spots and a circular array of six spots surrounding a central spot, are sequentially irradiated. Pennes bio-heat transfer model is used as the governing equation. Finite volume method is applied to find the temperature distribution due to laser irradiation inside the human eye. Each spot is heated for 100 ms and subsequently cooled for 100 ms with an initial laser power of 0.2 W. Based on the outcome of… More >

Anas Bilal¹, Azhar Imran², Talha Imtiaz Baig^3,4, Xiaowen Liu^1,*, Haixia Long¹, Abdulkareem Alzahrani⁵, Muhammad Shafiq⁶

Computer Systems Science and Engineering, Vol.48, No.2, pp. 511-528, 2024, DOI:10.32604/csse.2023.039672

Abstract Artificial Intelligence (AI) is being increasingly used for diagnosing Vision-Threatening Diabetic Retinopathy (VTDR), which is a leading cause of visual impairment and blindness worldwide. However, previous automated VTDR detection methods have mainly relied on manual feature extraction and classification, leading to errors. This paper proposes a novel VTDR detection and classification model that combines different models through majority voting. Our proposed methodology involves preprocessing, data augmentation, feature extraction, and classification stages. We use a hybrid convolutional neural network-singular value decomposition (CNN-SVD) model for feature extraction and selection and an improved SVM-RBF with a Decision Tree (DT) and K-Nearest Neighbor (KNN)… More >

Sijia Zhu^1,*, Pinxiu Wang², Ke Shen¹

CMC-Computers, Materials & Continua, Vol.78, No.1, pp. 283-302, 2024, DOI:10.32604/cmc.2023.045506

Abstract This paper proposes a new network structure, namely the ProNet network. Retinal medical image segmentation can help clinical diagnosis of related eye diseases and is essential for subsequent rational treatment. The baseline model of the ProNet network is UperNet (Unified perceptual parsing Network), and the backbone network is ConvNext (Convolutional Network). A network structure based on depth-separable convolution and 1 × 1 convolution is used, which has good performance and robustness. We further optimise ProNet mainly in two aspects. One is data enhancement using increased noise and slight angle rotation, which can significantly increase the diversity of data and help… More >

D. Dorathy Prema Kavitha¹, L. Francis Raj¹, Sandeep Kautish^2,#, Abdulaziz S. Almazyad³, Karam M. Sallam⁴, Ali Wagdy Mohamed^5,6,*

CMES-Computer Modeling in Engineering & Sciences, Vol.139, No.1, pp. 801-816, 2024, DOI:10.32604/cmes.2023.030902

Abstract The intuitive fuzzy set has found important application in decision-making and machine learning. To enrich and utilize the intuitive fuzzy set, this study designed and developed a deep neural network-based glaucoma eye detection using fuzzy difference equations in the domain where the retinal images converge. Retinal image detections are categorized as normal eye recognition, suspected glaucomatous eye recognition, and glaucomatous eye recognition. Fuzzy degrees associated with weighted values are calculated to determine the level of concentration between the fuzzy partition and the retinal images. The proposed model was used to diagnose glaucoma using retinal images and involved utilizing the Convolutional… More >

JING LI^1,2, WANWAN FAN⁴, LILI HAO¹, YONGSHENG LI⁵, GUOCHENG YU¹, WEI SUN⁶, XIANQIONG LUO^2,*, JINGXIANG ZHONG^1,3,*

BIOCELL, Vol.47, No.11, pp. 2485-2494, 2023, DOI:10.32604/biocell.2023.044177

Abstract Objective: This study aimed to investigate the potential of human umbilical cord mesenchymal stem cell (hucMSC)-derived exosomes (hucMSC-Exos) in inhibiting hypoxia-induced cell hyper proliferation and overexpression of vascular endothelial growth factor A (VEGF-A) in immature human fetal retinal microvascular endothelial cells (hfRMECs). Methods: Exosomes were isolated from hucMSCs using cryogenic ultracentrifugation and characterized through various techniques, including transmission electron microscopy, nanoparticle tracking analysis, bicinchoninic acid assays, and western blotting. The hfRMECs were identified using von Willebrand factor (vWF) co-staining and divided into four groups: a control group cultured under normoxic condition, a hypoxic model group, a hypoxic group treated with… More > Graphic Abstract

Wenran Jia¹, Simin Ma¹, Peng Geng¹, Yan Sun^2,*

CMC-Computers, Materials & Continua, Vol.76, No.3, pp. 3393-3411, 2023, DOI:10.32604/cmc.2023.040091

Abstract Retinal vessel segmentation in fundus images plays an essential role in the screening, diagnosis, and treatment of many diseases. The acquired fundus images generally have the following problems: uneven illumination, high noise, and complex structure. It makes vessel segmentation very challenging. Previous methods of retinal vascular segmentation mainly use convolutional neural networks on U Network (U-Net) models, and they have many limitations and shortcomings, such as the loss of microvascular details at the end of the vessels. We address the limitations of convolution by introducing the transformer into retinal vessel segmentation. Therefore, we propose a hybrid method for retinal vessel… More >

Krishna Santosh Naidana, Soubhagya Sankar Barpanda^*

Computer Systems Science and Engineering, Vol.47, No.1, pp. 699-720, 2023, DOI:10.32604/csse.2023.036744

Abstract Glaucoma is a group of ocular atrophy diseases that cause progressive vision loss by affecting the optic nerve. Because of its asymptomatic nature, glaucoma has become the leading cause of human blindness worldwide. In this paper, a novel computer-aided diagnosis (CAD) approach for glaucomatous retinal image classification has been introduced. It extracts graph-based texture features from structurally improved fundus images using discrete wavelet-transformation (DWT) and deterministic tree-walk (DTW) procedures. Retinal images are considered from both public repositories and eye hospitals. Images are enhanced with image-specific luminance and gradient transitions for both contrast and texture improvement. The enhanced images are mapped… More >

V. Banupriya^1,*, S. Anusuya²

CMC-Computers, Materials & Continua, Vol.75, No.3, pp. 5597-5613, 2023, DOI:10.32604/cmc.2023.038696

Abstract In the modern world, one of the most severe eye infections brought on by diabetes is known as diabetic retinopathy (DR), which will result in retinal damage, and, thus, lead to blindness. Diabetic retinopathy (DR) can be well treated with early diagnosis. Retinal fundus images of humans are used to screen for lesions in the retina. However, detecting DR in the early stages is challenging due to the minimal symptoms. Furthermore, the occurrence of diseases linked to vascular anomalies brought on by DR aids in diagnosing the condition. Nevertheless, the resources required for manually identifying the lesions are high. Similarly,… More >

Muwei Jian^1,2,#,*, Ronghua Wu^1,#, Hongyu Chen¹, Lanqi Fu³, Chengdong Yang¹

CMES-Computer Modeling in Engineering & Sciences, Vol.137, No.1, pp. 705-716, 2023, DOI:10.32604/cmes.2023.027425

Abstract In intelligent perception and diagnosis of medical equipment, the visual and morphological changes in retinal vessels are closely related to the severity of cardiovascular diseases (e.g., diabetes and hypertension). Intelligent auxiliary diagnosis of these diseases depends on the accuracy of the retinal vascular segmentation results. To address this challenge, we design a Dual-Branch-UNet framework, which comprises a Dual-Branch encoder structure for feature extraction based on the traditional U-Net model for medical image segmentation. To be more explicit, we utilize a novel parallel encoder made up of various convolutional modules to enhance the encoder portion of the original U-Net. Then, image… More >

Aqsa Aslam, Saima Farhan^*, Momina Abdul Khaliq, Fatima Anjum, Ayesha Afzaal, Faria Kanwal

Intelligent Automation & Soft Computing, Vol.36, No.3, pp. 2607-2622, 2023, DOI:10.32604/iasc.2023.034041

Abstract Use of deep learning algorithms for the investigation and analysis of medical images has emerged as a powerful technique. The increase in retinal diseases is alarming as it may lead to permanent blindness if left untreated. Automation of the diagnosis process of retinal diseases not only assists ophthalmologists in correct decision-making but saves time also. Several researchers have worked on automated retinal disease classification but restricted either to hand-crafted feature selection or binary classification. This paper presents a deep learning-based approach for the automated classification of multiple retinal diseases using fundus images. For this research, the data has been collected… More >