MARÍA B. ESPINOSA2 , NICOLÁS A. FRAUNHOFFER1 , NOELIA P. LEOPARDO1 , ALFREDO D. VITULLO2 AND MIGUEL A. WILLIS1
BIOCELL, Vol.35, No.2, pp. 37-42, 2011, DOI:10.32604/biocell.2011.35.037
Abstract Lagostomus maximus is a notable mammalian model for reproductive studies. Females have
an extremely high ovulation rate, which is due to down-regulation of the follicular apoptosis pathway, which
ensures a large pool of developing follicles. This large pool is supported by the convoluted anatomy of the
mature ovary, whose germinal tissue is found in irregularly curved ridges throughout the cortex. Medullary
tissue is restricted to a minimum. Lyso Tracker Red reconstruction under confocal laser scanning microscopy
was used to recognize and measure all follicular stages from primordial to antral. Unlike most mammals in
which early primordial follicles are just found… More >
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