J. S. Ren^*

Molecular & Cellular Biomechanics, Vol.4, No.1, pp. 55-66, 2007, DOI:10.3970/mcb.2007.004.055

Abstract Formation and rupture of aneurysms due to the inflation of an artery with collagen fibers distributed in two preferred directions, subjected to internal pressure and axial stretch are examined within the framework of nonlinear elasticity. A two layer tube model with a fiber-reinforced composite based incompressible anisotropic hyperelastic constitutive material is employed to model the stress-strain behavior of the artery wall with distributed collagen fibers. The artery wall takes up a uniform inflation deformation, and there are no aneurysms in the artery under the normal condition. But an aneurysm may be formed in arteries when… More >

Chun Yang^1,2, Dalin Tang^2,3 Satya Atluri⁴

CMES-Computer Modeling in Engineering & Sciences, Vol.57, No.1, pp. 51-76, 2010, DOI:10.3970/cmes.2010.057.051

Abstract Cardiovascular disease (CVD) is becoming the number one cause of death worldwide. Atherosclerotic plaque rupture and progression are closely related to most severe cardiovascular syndromes such as heart attack and stroke. Mechanisms governing plaque rupture and progression are not well understood. A computational procedure based on three-dimensional meshless generalized finite difference (MGFD) method and serial magnetic resonance imaging (MRI) data was introduced to quantify patient-specific carotid atherosclerotic plaque growth functions and simulate plaque progression. Participating patients were scanned three times (T1, T2, and T3, at intervals of about 18 months) to obtain plaque progression data.… More >

Chun Yang¹, Dalin Tang², Chun Yuan³, William Kerwin², Fei Liu³, Gador Canton³, Thomas S. Hatsukami^3,4, Satya Atluri⁵

CMES-Computer Modeling in Engineering & Sciences, Vol.28, No.2, pp. 95-108, 2008, DOI:10.3970/cmes.2008.028.095

Abstract Atherosclerotic plaque rupture and progression have been the focus of intensive investigations in recent years. Plaque rupture is closely related to most severe cardiovascular syndromes such as heart attack and stroke. A computational procedure based on meshless generalized finite difference (MGFD) method and serial magnetic resonance imaging (MRI) data was introduced to quantify patient-specific carotid atherosclerotic plaque growth functions and simulate plaque progression. Participating patients were scanned three times (T₁,T₂, and T₃, at intervals of about 18 months) to obtain plaque progression data. Vessel wall thickness (WT) changes were used as the measure for plaque progression.… More >

M.El-Gammal¹, J.M.Floryan¹

FDMP-Fluid Dynamics & Materials Processing, Vol.2, No.1, pp. 17-26, 2006, DOI:10.3970/fdmp.2006.002.017

Abstract Interface deformation and thermocapillary rupture in a cavity with free upper surface subject to concentrated heating from above is investigated. The dynamics of the process is modulated by placing different amounts of liquid in the cavity. The results determined for large Biot and zero Marangoni numbers show the existence of limit points beyond which steady, continuous interface cannot exist and processes leading to the interface rupture develop. Evolution of the limit point as a function of the mass of the liquid is investigated. The topology of the flow field is found to be qualitatively similar, More >

K. Khanna^1,2, V.K. Gupta³, S.P. Nigam¹

CMC-Computers, Materials & Continua, Vol.48, No.3, pp. 147-161, 2015, DOI:10.3970/cmc.2015.048.147

Abstract A mathematical model is developed to describe the steady state creep in a rotating Al-SiC_p disc having a non-linear thickness profile and distribution of SiC particles along the radial direction. The model is used to investigate the effect of imposing three different kinds of radial temperature profiles viz. linear, parabolic and exponential with fixed values of inner and outer surface temperatures, on the creep stresses and strain rates. It is noticed that by increasing the temperature exponent (n_T), the radial stress (over the entire radius) and tangential stress (near the inner radius) increase in the disc.… More >

Linsen Zhu¹, Jiang Zhou², Xuejun Fan²

CMC-Computers, Materials & Continua, Vol.39, No.2, pp. 113-134, 2014, DOI:10.3970/cmc.2014.039.113

Abstract In this paper, a damage mechanics-based continuum theory is developed for the coupled analysis of moisture vaporization, moisture absorption and desorption, heat conduction, and mechanical stress for a reflow process in microelectronic devices. The extremely compliant film has been used in wafer level lamination process. Such a soft film experiences cohesive rupture subjected to moisture absorption during reflow. The numerical simulation results have demonstrated that vapor pressure due to moisture vaporization is the dominant driving force for the failures. The correlation between the vapor pressure evolution and the film rupture observed from the experiments have… More >