Xiuqing Qian1,2, Fan yuan1,*
Molecular & Cellular Biomechanics, Vol.16, Suppl.2, pp. 89-89, 2019, DOI:10.32604/mcb.2019.07041
Abstract Elevated intraocular pressure (IOP) is the most important risk factor for disease progression in glaucoma patients. The elevation is predominantly due to the increase in the aqueous outflow resistance in the trabecular outflow pathway. Recent data have shown that the resistance increase is correlated with changes in the tissue stiffness. To this end, we developed a mathematical model to simulate how the tissue stiffness can affect the deformation of the trabecular meshwork (TM) that can be determined experimentally. The goal of the study is to develop a method to non-invasively determine the TM stiffness in patients through measurement of the… More >
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