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  • Open Access

    ARTICLE

    Anatomic Correlates of Mitral Systolic Anterior Motion in Transposition of the Great Arteries Following Atrial Switch Operation

    Norman Aiad1,2,3,7, Mark V. Sherrid1,7, Adam J. Small1, Youssef Elnabawi1,7, Jodi Feinberg1, Leon Axel1,4, Ralph Mosca5, T. K. Susheel Kumar5, Michael Argilla6, Dan G. Halpern1,7,*

    Congenital Heart Disease, Vol.18, No.3, pp. 267-277, 2023, DOI:10.32604/chd.2023.025853

    Abstract Introduction: We sought to investigate whether the development of sub-pulmonic systolic anterior motion (SAM) may be inherent to the anatomy of the the mitral valve (MV) or affected by external factors, such as a dilated right ventricle or chest abnormalities in d-looped transposition of the great arteries post atrial switch operation (d-TGA/AtS). Methods: Analysis was performed of clinical and cardiac imaging studies acquired on 19 adult patients with d-TGA/AtS (age 42 ± 6 years old, 56% male) between 2015–2019. Echocardiography data included mitral apparatus anatomy, and CT/MRI data included biventricular dimensions, function, and Haller index (HI) for pectus deformity. Results:More >

  • Open Access

    ARTICLE

    NT-proBNP predicts mortality in adults with transposition of the great arteries late after Mustard or Senning correction

    Jana Rubáčková Popelová, MD1,2 | Markéta Tomková1,3 | Jakub Tomek1,4

    Congenital Heart Disease, Vol.12, No.4, pp. 448-457, 2017, DOI:10.1111/chd.12466

    Abstract Objective: The patients after Mustard and Senning corrections of transposition of the great arteries (TGA) are at an increased risk of unexpected death. The aim of this study was to identify markers allowing risk stratification of patients after atrial switch correction of TGA to provide them with optimum care.
    Methods and Results: In this study, 87 patients were retrospectively evaluated after atrial switch correction of TGA followed-up between 2005 and 2015. The mortality during the follow-up was 9% (8 cardiac deaths). Markers significantly predictive of death using univariable Cox proportional hazard ratio survival analysis were: N-terminal pro-B-type natriuretic peptide (NT-proBNP),… More >

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