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  • Open Access

    ARTICLE

    Cost-Sensitive Dual-Stream Residual Networks for Imbalanced Classification

    Congcong Ma1,2, Jiaqi Mi1, Wanlin Gao1,2, Sha Tao1,2,*

    CMC-Computers, Materials & Continua, Vol.80, No.3, pp. 4243-4261, 2024, DOI:10.32604/cmc.2024.054506

    Abstract Imbalanced data classification is the task of classifying datasets where there is a significant disparity in the number of samples between different classes. This task is prevalent in practical scenarios such as industrial fault diagnosis, network intrusion detection, cancer detection, etc. In imbalanced classification tasks, the focus is typically on achieving high recognition accuracy for the minority class. However, due to the challenges presented by imbalanced multi-class datasets, such as the scarcity of samples in minority classes and complex inter-class relationships with overlapping boundaries, existing methods often do not perform well in multi-class imbalanced data… More >

  • Open Access

    ARTICLE

    Microstructure and Hot Tearing Sensitivity Simulation and Parameters Optimization for the Centrifugal Casting of Al-Cu Alloy

    Xueli He1,, Shengkun Lv1,, Ruifeng Dou1,*, Yanying Zhang1, Junsheng Wang2, Xunliang Liu1, Zhi Wen1

    CMC-Computers, Materials & Continua, Vol.80, No.2, pp. 2873-2895, 2024, DOI:10.32604/cmc.2024.052571

    Abstract Four typical theories on the formation of thermal tears: strength, liquid film, intergranular bridging, and solidification shrinkage compensation theories. From these theories, a number of criteria have been derived for predicting the formation of thermal cracks, such as the stress-based Niyama, Clyne, and RDG (Rapaz-Dreiser-Grimaud) criteria. In this paper, a mathematical model of horizontal centrifugal casting was established, and numerical simulation analysis was conducted for the centrifugal casting process of cylindrical Al-Cu alloy castings to investigate the effect of the centrifugal casting process conditions on the microstructure and hot tearing sensitivity of alloy castings by… More >

  • Open Access

    ARTICLE

    Enhanced Transmission Tower Foundation Reliability Assessment: A Fuzzy Comprehensive Evaluation Framework

    Yang Li1, Zikang Zheng1,*, Jiangkun Zhang2

    Structural Durability & Health Monitoring, Vol.18, No.4, pp. 425-444, 2024, DOI:10.32604/sdhm.2024.046584

    Abstract Due to the lack of a quantitative basis for the inspection, evaluation, and identification of existing transmission tower foundations, a new fuzzy comprehensive evaluation method is proposed to assess the reliability of transmission tower foundation bearing capacity. This method is based on the reliability analysis of the transmission tower foundation bearing capacity by analyzing the sensitivity of degradation of detection indexes on the reliability of transmission tower foundation bearing capacity, the weighting coefficient matrix is established about the influencing factors in the evaluation model. Through the correlation analysis between the bearing capacity degradation of the More > Graphic Abstract

    Enhanced Transmission Tower Foundation Reliability Assessment: A Fuzzy Comprehensive Evaluation Framework

  • Open Access

    ARTICLE

    Evaluation of Well Spacing for Primary Development of Fractured Horizontal Wells in Tight Sandstone Gas Reservoirs

    Fang Li1,*, Juan Wu1, Haiyong Yi2, Lihong Wu2, Lingyun Du1, Yuan Zeng1

    FDMP-Fluid Dynamics & Materials Processing, Vol.20, No.5, pp. 1015-1030, 2024, DOI:10.32604/fdmp.2023.043256

    Abstract Methods for horizontal well spacing calculation in tight gas reservoirs are still adversely affected by the complexity of related control factors, such as strong reservoir heterogeneity and seepage mechanisms. In this study, the stress sensitivity and threshold pressure gradient of various types of reservoirs are quantitatively evaluated through reservoir seepage experiments. On the basis of these experiments, a numerical simulation model (based on the special seepage mechanism) and an inverse dynamic reserve algorithm (with different equivalent drainage areas) were developed. The well spacing ranges of Classes I, II, and III wells in the Q gas More > Graphic Abstract

    Evaluation of Well Spacing for Primary Development of Fractured Horizontal Wells in Tight Sandstone Gas Reservoirs

  • Open Access

    ARTICLE

    Sensitivity Analysis of Electromagnetic Scattering from Dielectric Targets with Polynomial Chaos Expansion and Method of Moments

    Yujing Ma1,4, Zhongwang Wang2, Jieyuan Zhang3, Ruijin Huo1,4, Xiaohui Yuan1,4,*

    CMES-Computer Modeling in Engineering & Sciences, Vol.140, No.2, pp. 2079-2102, 2024, DOI:10.32604/cmes.2024.048488

    Abstract In this paper, an adaptive polynomial chaos expansion method (PCE) based on the method of moments (MoM) is proposed to construct surrogate models for electromagnetic scattering and further sensitivity analysis. The MoM is applied to accurately solve the electric field integral equation (EFIE) of electromagnetic scattering from homogeneous dielectric targets. Within the bistatic radar cross section (RCS) as the research object, the adaptive PCE algorithm is devoted to selecting the appropriate order to construct the multivariate surrogate model. The corresponding sensitivity results are given by the further derivative operation, which is compared with those of More >

  • Open Access

    ARTICLE

    A comparative in vitro study on the effect of SGLT2 inhibitors on chemosensitivity to doxorubicin in MCF-7 breast cancer cells

    SHAHID KARIM1,*, ALANOUD NAHER ALGHANMI1, MAHA JAMAL1, HUDA ALKREATHY1, ALAM JAMAL2, HIND A. ALKHATABI3, MOHAMMED BAZUHAIR1, AFTAB AHMAD4,5

    Oncology Research, Vol.32, No.5, pp. 817-830, 2024, DOI:10.32604/or.2024.048988

    Abstract Cancer frequently develops resistance to the majority of chemotherapy treatments. This study aimed to examine the synergistic cytotoxic and antitumor effects of SGLT2 inhibitors, specifically Canagliflozin (CAN), Dapagliflozin (DAP), Empagliflozin (EMP), and Doxorubicin (DOX), using in vitro experimentation. The precise combination of CAN+DOX has been found to greatly enhance the cytotoxic effects of doxorubicin (DOX) in MCF-7 cells. Interestingly, it was shown that cancer cells exhibit an increased demand for glucose and ATP in order to support their growth. Notably, when these medications were combined with DOX, there was a considerable inhibition of glucose consumption, as More > Graphic Abstract

    A comparative <i>in vitro</i> study on the effect of SGLT2 inhibitors on chemosensitivity to doxorubicin in MCF-7 breast cancer cells

  • Open Access

    ARTICLE

    Aggravation of Cancer, Heart Diseases and Diabetes Subsequent to COVID-19 Lockdown via Mathematical Modeling

    Fatma Nese Efil1, Sania Qureshi1,2,3, Nezihal Gokbulut1,4, Kamyar Hosseini1,3, Evren Hincal1,4,*, Amanullah Soomro2

    CMES-Computer Modeling in Engineering & Sciences, Vol.140, No.1, pp. 485-512, 2024, DOI:10.32604/cmes.2024.047907

    Abstract The global population has been and will continue to be severely impacted by the COVID-19 epidemic. The primary objective of this research is to demonstrate the future impact of COVID-19 on those who suffer from other fatal conditions such as cancer, heart disease, and diabetes. Here, using ordinary differential equations (ODEs), two mathematical models are developed to explain the association between COVID-19 and cancer and between COVID-19 and diabetes and heart disease. After that, we highlight the stability assessments that can be applied to these models. Sensitivity analysis is used to examine how changes in… More >

  • Open Access

    ARTICLE

    Analysis of the Relationships between Noise Exposure and Stress/Arousal Mood at Different Levels of Workload

    Rohollah Fallah Madvari1, Hamideh Bidel2, Ahmad Mehri3, Fatema Babaee4, Fereydoon Laal5,*

    Sound & Vibration, Vol.58, pp. 119-131, 2024, DOI:10.32604/sv.2024.048861

    Abstract Noise is one of the environmental factors with mental and physical effects. The workload is also the multiple mental and physical demands of the task. Therefore, his study investigated the relationship between noise exposure and mood states at different levels of workload. The study recruited 50 workers from the manufacturing sector (blue-collar workers) as the exposed group and 50 workers from the office sector (white-collar workers) as the control group. Their occupational noise exposure was measured by dosimetry. The Stress-Arousal Checklist (SACL) and the NASA Task Load Index (NASA-TLX) were used to measure mood and… More >

  • Open Access

    ARTICLE

    A Hybrid SIR-Fuzzy Model for Epidemic Dynamics: A Numerical Study

    Muhammad Shoaib Arif1,2,*, Kamaleldin Abodayeh1, Yasir Nawaz2

    CMES-Computer Modeling in Engineering & Sciences, Vol.139, No.3, pp. 3417-3434, 2024, DOI:10.32604/cmes.2024.046944

    Abstract This study focuses on the urgent requirement for improved accuracy in disease modeling by introducing a new computational framework called the Hybrid SIR-Fuzzy Model. By integrating the traditional Susceptible-Infectious-Recovered (SIR) model with fuzzy logic, our method effectively addresses the complex nature of epidemic dynamics by accurately accounting for uncertainties and imprecisions in both data and model parameters. The main aim of this research is to provide a model for disease transmission using fuzzy theory, which can successfully address uncertainty in mathematical modeling. Our main emphasis is on the imprecise transmission rate parameter, utilizing a three-part… More >

  • Open Access

    ARTICLE

    Leveraging diverse cell-death patterns to predict the clinical outcome of immune checkpoint therapy in lung adenocarcinoma: Based on muti-omics analysis and vitro assay

    HONGYUAN LIANG1,#, YANQIU LI2,#, YONGGANG QU3, LINGYUN ZHANG4,*

    Oncology Research, Vol.32, No.2, pp. 393-407, 2024, DOI:10.32604/or.2023.031134

    Abstract Advanced LUAD shows limited response to treatment including immune therapy. With the development of sequencing omics, it is urgent to combine high-throughput multi-omics data to identify new immune checkpoint therapeutic response markers. Using GSE72094 (n = 386) and GSE31210 (n = 226) gene expression profile data in the GEO database, we identified genes associated with lung adenocarcinoma (LUAD) death using tools such as “edgeR” and “maftools” and visualized the characteristics of these genes using the “circlize” R package. We constructed a prognostic model based on death-related genes and optimized the model using LASSO-Cox regression methods.… More >

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