Hasan Kaan Kucukerdem^*

Phyton-International Journal of Experimental Botany, Vol.95, No.1, 2026, DOI:10.32604/phyton.2026.074188 - 30 January 2026

Abstract Root-zone temperature (RZT) strongly affects plant growth, nutrient uptake and tolerance to environmental stress, making its regulation a key challenge in greenhouse cultivation in cold climates. This study aimed to assess the potential of passive techniques, namely black polyethylene mulch and row covers, for modifying RZT dynamics in lettuce (Lactuca sativa L.) production and to evaluate the predictive performance of the eXtreme Gradient Boosting (XGBoost) algorithm. Experiments were conducted in Iğdır, Türkiye, over a 61-day period, with soil temperature continuously monitored at depths of 1–30 cm under mulched and non-mulched conditions, alongside measurements of greenhouse air… More >

Yuerou Feng, Panpan Tong, Shuwen Fu, Xiaofan Lu, Liquan Zheng, Jielan Lai^*, Renchun Lai^*

Oncology Research, Vol.34, No.2, 2026, DOI:10.32604/or.2025.072563 - 19 January 2026

Abstract Background: The efficacy of standard 5-fluorouracil (5-FU) chemotherapy for colorectal cancer is limited by drug resistance and adverse effects, prompting research into esketamine, a potent ketamine variant with analgesic, antidepressant, and recently discovered anti-tumor properties, to determine if it can enhance 5-FU’s chemosensitivity. This study investigates whether esketamine synergizes with 5-FU to enhance therapeutic efficacy in colorectal adenocarcinoma cell models. Methods: We performed functional assays to evaluate proliferation (CCK-8), migration (wound healing), invasion (Transwell), and apoptosis (flow cytometry) in colorectal adenocarcinoma cell lines treated with 5-FU alone or in combination with esketamine. Transcriptomic profiling was… More >

Zezhi Wen¹, Kai Zhang¹, Shanlin Liang², Liqiong Chen^1,*, Zijian Xiong¹

Structural Durability & Health Monitoring, Vol.20, No.1, 2026, DOI:10.32604/sdhm.2025.066408 - 08 January 2026

Abstract Maintaining the structural integrity of parallel natural gas pipelines during leakage-induced jet fires remains a critical engineering challenge. Existing methods often fail to account for the complex interactions among heat transfer, material behavior, and pipeline geometry, which can lead to overly simplified and potentially unsafe assessments. To address these limitations, this study develops a multiphysics approach that integrates small-orifice leakage theory with detailed thermo-fluid-structural simulations. The proposed framework contributes to a more accurate failure analysis through three main components: (1) coupled modeling that tracks transient heat flow and stress development as fire conditions evolve; (2)… More >

Jing Cai^1,#, Haoyun Zhu^1,#, Weiling Guo¹, Ting Huang¹, Pangzhou Chen^1,2, Wen Zhou¹, Ziyun Guan^1,3,*

Oncology Research, Vol.34, No.1, 2026, DOI:10.32604/or.2025.069902 - 30 December 2025

Abstract Background: Therapeutic responses of breast cancer vary among patients and lead to drug resistance and recurrence due to the heterogeneity. Current preclinical models, however, are inadequate for predicting individual patient responses towards different drugs. This study aimed to investigate the patient-derived breast cancer culture models for drug sensitivity evaluations. Methods: Tumor and adjacent tissues from female breast cancer patients were collected during surgery. Patient-derived breast cancer cells were cultured using the conditional reprogramming technique to establish 2D models. The obtained patient-derived conditional reprogramming breast cancer (CRBC) cells were subsequently embedded in alginate-gelatin methacryloyl hydrogel microspheres… More >

Zhongrui Jing¹, Hongzhang Yang^1,*, Jiangpu Guo²

CMC-Computers, Materials & Continua, Vol.86, No.2, pp. 1-25, 2026, DOI:10.32604/cmc.2025.067759 - 09 December 2025

Abstract Hard disk drives (HDDs) serve as the primary storage devices in modern data centers. Once a failure occurs, it often leads to severe data loss, significantly degrading the reliability of storage systems. Numerous studies have proposed machine learning-based HDD failure prediction models. However, the Self-Monitoring, Analysis, and Reporting Technology (SMART) attributes differ across HDD manufacturers. We define hard drives of the same brand and model as homogeneous HDD groups, and those from different brands or models as heterogeneous HDD groups. In practical engineering scenarios, a data center is often composed of a heterogeneous population of… More >

Hameed H. Ahmed¹, Thaer A. Mezher^2,*, Marwan R. Rashid³

Chalcogenide Letters, Vol.22, No.12, pp. 1055-1066, 2025, DOI:10.15251/CL.2025.2212.1055 - 10 December 2025

Abstract Laser ablation in liquids (LAL), a hygienic and effective method for creating high-purity nanomaterials, was used in this study to create cadmium sulfide (CdS) and silver oxide (Ag₂O) nanoparticles. The sputtering process was used to deposit the produced nanomaterials on porous silicon (PSi) substrates, and a number of assays were used to examine the samples’ structural, optical, and electrical characteristics. The CdS sample had a hexagonal crystal structure, according to X-ray diffraction (XRD) data, whereas the AgO sample had a cubic structure. The diameters of the nanoparticles in the two samples ranged from 22.64 nm for… More >

Jinyou Qiu^1,2, Jiale Liu^1,2, Yubing Li^1,2,*, Shaogeng Zhong³, Guilong Dai^1,2, Wenhua Liu⁴

Frontiers in Heat and Mass Transfer, Vol.23, No.6, pp. 2025-2049, 2025, DOI:10.32604/fhmt.2025.072260 - 31 December 2025

Abstract The growing demand for energy-saving and renewable heating solutions has made photovoltaic/thermal (PV/T) heat pump systems a promising technology. However, their thermal and electrical performance, as well as the overall utilization of solar energy, strongly depend on capacity configuration and operating parameters. To address this issue, this study proposes a PV/T heat pump system featuring a novel rhombic flow channel structure that functions as the collector-evaporator. An experimental test bench was established to evaluate system performance, and a one-dimensional numerical model was developed to investigate the effects of environmental and operating parameters. The simulation results… More > Graphic Abstract

Mujahid Islam¹, Fateh Ali^1,*, Xinlong Feng^1,*, M. Zahid², Sana Naz Maqbool¹

CMES-Computer Modeling in Engineering & Sciences, Vol.145, No.3, pp. 3511-3561, 2025, DOI:10.32604/cmes.2025.073678 - 23 December 2025

Abstract Roll coating is a vital industrial process used in printing, packaging, and polymer film production, where maintaining a uniform coating is critical for product quality and efficiency. This work models non-isothermal Carreau fluid flow between a rotating roll and a stationary wall under fixed boundary constraints to evaluate how non-Newtonian and thermal effects influence coating performance. The governing equations are transformed into non-dimensional form and simplified using lubrication approximation theory. Approximate analytical solutions are obtained via the perturbation technique, while numerical results are computed using both the finite difference method and the BVP-Midrich technique. Furthermore, More >

Sh. B. Utamuradova^a, F. A. Giyasova^b, M. S. Paizullakhanov^c, S. Yu. Gerasimenko^d, M. A. Yuldoshev^e,g,*, S. R. Boydedayev^g, M. R. Bekchanova^h

Chalcogenide Letters, Vol.22, No.8, pp. 753-764, 2025, DOI:10.15251/CL.2025.228.753

Abstract Based on the experimental data, the results of the study of photoelectric and gain characteristics of modified multi-barrier photodiode Au-nCdS-nSi-pCdTe-Au structures are presented, which are obtained by the method of vacuum evaporation in a quasi-closed volume by sputtering cadmium sulfide and cadmium telluride layers on a silicon substrate with a specific resistance of 607.47 Ohm⋅cm. It is shown that the structures in the passing direction of the current at low illumination levels operate as injection photodiodes, and also the optical spectral range (0.3÷0.95 μm) covers from the nSi-pCdTe-Au side and (1.0÷1.4 μm) from the Au-nCdS-nSi More >

Rym Akrout¹, Ludovic Leloup², Khouloud Ayed¹, Fabrice Parat², Sami Zekri^3,4, Wassim Y. Almawi¹, Rahma Boughriba¹, Hanen Attia¹, Olfa Masmoudi-Kouki⁴, Hervé Kovacic^2,*, Asma Gati^1,*

Oncology Research, Vol.33, No.12, pp. 3887-3906, 2025, DOI:10.32604/or.2025.070729 - 27 November 2025

Abstract Objectives: Cisplatin (CDDP) therapy for glioblastoma (GBM) is linked with several limitations, which include poor penetration of the blood-brain barrier (BBB), systemic toxicity, and the development of drug resistance mechanisms implicating oxidative stress dysregulation and compromised apoptotic pathways. This study evaluates C-Phycocyanin (C-PC) as a potential adjuvant to enhance CDDP efficacy by modulating redox balance and apoptosis. Methods: GBM cells (U87 and U87-EGFRvIII) were treated with CDDP, C-PC, or their combination. Cell viability was assessed by MTT assay; apoptosis was evaluated by DAPI staining and Western blot analysis of cleaved Caspase-3 and poly (ADP-ribose) polymerase… More > Graphic Abstract