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  • Open Access

    ARTICLE

    SARS-CoV-2 Vaccine-Induced Seroconversion and Immune Correlates in Patients with Hematological Malignancies. A Real World Study

    Norbert Nass1,2,#, Mohamad-Kamal Yaakoub1,#, Alexandra-Victorita Simion3, Hartmut Kroll4, Sabine Westphal3, Judith Pannier1, Gerhard Behre1,*

    Oncology Research, Vol.33, No.10, pp. 2923-2935, 2025, DOI:10.32604/or.2025.067561 - 26 September 2025

    Abstract Background: Patients with hemato-oncological malignancies may respond insufficiently to vaccination, especially in terms of antibody titer. The antibody response depends on the type of malignancy as well as the type and timing of treatment. We intended to evaluate this using real-world data from patients of our regional hospital. This study also considers the role of immune status, including T-cell activation markers, in predicting vaccination success. Methods: Seventeen patients of our hospital having a hematological malignancy were included in this study, including myeloma, lymphoma, as well as acute myeloid leukemia (AML) and chronic lymphoid leukemia (CLL).… More >

  • Open Access

    ARTICLE

    Coronavirus: A “Mild” Virus Turned Deadly Infection

    Rizwan Ali Naqvi1, Muhammad Faheem Mushtaq2, Natash Ali Mian3, Muhammad Adnan Khan4,*, Atta-ur-Rahman5, Muhammad Ali Yousaf6, Muhammad Umair6, Rizwan Majeed7

    CMC-Computers, Materials & Continua, Vol.67, No.2, pp. 2631-2646, 2021, DOI:10.32604/cmc.2021.012167 - 05 February 2021

    Abstract Coronaviruses are a family of viruses that can be transmitted from one person to another. Earlier strains have only been mild viruses, but the current form, known as coronavirus disease 2019 (COVID-19), has become a deadly infection. The outbreak originated in Wuhan, China, and has since spread worldwide. The symptoms of COVID-19 include a dry cough, sore throat, fever, and nasal congestion. Antimicrobial drugs, pathogen–host interaction, and 2 weeks of isolation have been recommended for the treatment of the infection. Safe operating procedures, such as the use of face masks, hand sanitizer, handwashing with soap,… More >

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