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  • Open Access

    ARTICLE

    FibroSURE and elastography poorly predict the severity of liver fibrosis in Fontan-associated liver disease

    Jessica L. Schachter1, Manisha Patel2, Samuel R. Horton3, A. Mike Devane4, Alex Ewing5, Gary A. Abrams6

    Congenital Heart Disease, Vol.13, No.5, pp. 764-770, 2018, DOI:10.1111/chd.12650

    Abstract Objective: As the population of patients with Fontan circulation surviving into adult‐ hood increases, hepatic cirrhosis has grown to be a significant cause of morbidity and mortality. Early detection of advanced hepatic fibrosis is imperative for proper inter‐ vention and consideration for heart or combined heart/liver transplantation. Noninvasive biomarkers and elastography have been evaluated for their diagnostic utility with variable results in the Fontan population.
    Design: The cohort included 14 patients age 26.4 SD 7.5 who underwent Fontan surgery. All patients were evaluated with FibroSURE, shear wave elastography (SWE), hepatic duplex sonography, and liver biopsy. Liver fibrosis… More >

  • Open Access

    ARTICLE

    Calcium content on apple fruit influences the severity of Penicillium expansum

    Guerrero-Prieto VM1, DI Berlanga-Reyes2, JL Jacobo-Cuellar1, C Guigón-Lopez3, DL Ojeda-Barrios4, GD Ávila-Quezada4, A Núñez-Barrios4, OA Hernández-Rodríguez4

    Phyton-International Journal of Experimental Botany, Vol.86, pp. 74-78, 2017, DOI:10.32604/phyton.2017.86.074

    Abstract Calcium content and damage severity of Penicillium expansum because of its high concentration on “Red Delicious” postharvest apples were evaluated during the 2012-2013 winter in Cuauhtemoc, Chih. Mexico. Fruit weight, diameter, total soluble solids, pulp firmness and starch index were also determined. Penicillium expansum was inoculated into two wounds of eight mm diameter and 10 mm depth, on a total of 20 apple fruits per treatment. The inoculum was 0.2 mL of a suspension containing 1×108 conidia/mL. After inoculation, apple fruit was stored at 0 °C and 90% relative humidity during five weeks. Treatments were: apple fruit with More >

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