Minliang Liu1, Liang Liang2, Xiaoying Lou3, Glen Iannucci3, Edward Chen3, Bradley Leshnower3, Wei Sun1,*
Molecular & Cellular Biomechanics, Vol.16, Suppl.2, pp. 53-53, 2019, DOI:10.32604/mcb.2019.07387
Abstract It is well known that mechanical properties of the aortic wall exhibit patient-specific variations. Recent experimental findings also suggest the aortic wall properties are highly region-specific [1-2]. Thus, in vivo heterogeneous (non-uniform) nonlinear mechanical properties of the aortic wall of individual patients needs to be noninvasively identified for accurate prediction of clinical events (e.g. aortic rupture).
In this study, we developed an inverse approach for identification of patient-specific non-uniform material properties of the aortic wall from gated 3D CT scans. This inverse approach leverages the fact that the in vivo transmural mean stress (tension) of the aortic wall is… More >
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