Congenital Heart Disease, Vol.20, Suppl.1, pp. 1-49, 2025

Abstract This article has no abstract. More >

Shun Maki^1,*, Satoshi Nakano¹, Taiki Haga², Takehiro Niitsu¹, Ikuya Ueta¹

Congenital Heart Disease, Vol.20, No.5, pp. 547-558, 2025, DOI:10.32604/chd.2025.072277 - 30 November 2025

Abstract Background: Considering the limited evidence for acute postoperative nutritional therapy for congenital heart disease (CHD), this study evaluated the effects of achieving enteral nutrition (EN) targets in the acute postoperative phase on clinical outcomes in infants after congenital heart surgery. Methods: This retrospective cohort study, conducted in a multivalent pediatric intensive care unit (PICU), enrolled infants aged ≤6 months following congenital heart surgery between April 2021 and March 2023. Based on the American Society for Parenteral and Enteral Nutrition guidelines, the EN target was defined as two-thirds of the resting energy expenditure with a protein intake… More >

Khanh Toan Nguyen^1,*, Thi Huong Pham^1,2, Van Lam Ngo¹, Thi Thuy My Nguyen¹, Thi Dao Nguyen¹, Khanh Hung Truong¹, Van Nhat Nguyen¹, Van Thanh Le¹, Ba Duc Ho¹, Thi Phuong Thao Nguyen¹, Thi Ha Phuong Nguyen¹, Thi My Linh Dinh¹, Thi Hong Anh Vo¹, Thi Thuy Phan¹, Thi Hai Yen Le¹, Thi Nhung Ngo¹, Khanh Ha Nguyen¹

Oncology Research, Vol.33, No.12, pp. 4013-4028, 2025, DOI:10.32604/or.2025.069281 - 27 November 2025

Abstract Objective: Patients with stage III non-small cell lung cancer (NSCLC) present with a heterogeneous disease profile and often require multifaceted treatment strategies. This research aimed to investigate the demographic features, therapeutic patterns, and survival outcomes of such patients in Vietnam. Methods: A retrospective descriptive study was conducted on 731 patients diagnosed with stage III NSCLC American Joint Committee on Cancer (AJCC) 8th edition, at Nghe An Oncology Hospital from January 2018 to August 2024. Descriptive statistics summarized baseline and treatment characteristics. We calculated progression-free survival (PFS) and overall survival (OS) through the Kaplan–Meier approach and… More >

Joon Yau Leong^1,*, Vignesh Prasad², Carlos J. Perez Kerkvliet¹, Andrew A. Wagner³, Richard E. Link⁴, Mihir S. Shah¹

Canadian Journal of Urology, Vol.32, No.5, pp. 469-475, 2025, DOI:10.32604/cju.2025.066348 - 30 October 2025

Abstract In recent years, the introduction of the Da Vinci Single Port (SP) robotic platform has opened new doors for the treatment of localized renal masses. This technology, particularly when utilized via a regionalized retroperitoneal (RP) approach, offers several distinct advantages that may improve patient recovery. These advantages include easier access to both anterior and posterior renal tumors, avoidance of the peritoneal cavity with complicating adhesions, and simplified supine positioning, potentially reducing the risk of musculoskeletal or nerve injuries. Yet, the learning curve for RP surgery remains steep due to the unfamiliarity of many surgeons with More >

Andrea Panunzio¹, Rossella Orlando¹, Federico Greco^2,3, Giovanni Mazzucato⁴, Floriana Luigina Rizzo¹, Serena Domenica D’Elia¹, Antonio Benito Porcaro⁵, Alessandro Antonelli⁵, Alessandro Tafuri^1,6,*

Canadian Journal of Urology, Vol.32, No.5, pp. 375-384, 2025, DOI:10.32604/cju.2025.066140 - 30 October 2025

Abstract Background: The Barthel Index (BI) measures the level of patient independence in activities of daily living. This review aims to summarize current evidence on the use of the BI in urology, highlighting its potential as a tool for assessing patients prior to surgery. Materials and methods: A comprehensive search of PubMed, Scopus, and Web of Science databases was conducted for studies evaluating the BI in patients undergoing urologic surgery, following Systematic Review and Meta-analyses (PRISMA) guidelines. The BI was investigated both as a descriptor of baseline or postoperative health status and a prognostic indicator. A qualitative… More >

Takeshi Toyozumi^1,*, Hideaki Shimada², Hisahiro Matsubara¹

Oncology Research, Vol.33, No.11, pp. 3185-3206, 2025, DOI:10.32604/or.2025.065818 - 22 October 2025

Abstract Cancer immunotherapy has long been established as an important treatment option for cancers. In particular, Immune Checkpoint Inhibitor (ICI) has been reported to be effective against various gastrointestinal cancers (esophageal cancer, gastric cancer, colorectal cancer); however, the treatment phase in which ICI should be used and how it should be incorporated into the treatment strategy vary depending on the cancer type being treated. Multiple clinical trials and basic research on ICIs are currently underway, and new insights from these results will continue to change the clinical treatment strategy of gastrointestinal cancers. While it is desirable… More >

Batyrkhan Omarov^1,2,3,4,*

CMC-Computers, Materials & Continua, Vol.85, No.2, pp. 2195-2253, 2025, DOI:10.32604/cmc.2025.064799 - 23 September 2025

Abstract Deep learning now underpins many state-of-the-art systems for biomedical image and signal processing, enabling automated lesion detection, physiological monitoring, and therapy planning with accuracy that rivals expert performance. This survey reviews the principal model families as convolutional, recurrent, generative, reinforcement, autoencoder, and transfer-learning approaches as emphasising how their architectural choices map to tasks such as segmentation, classification, reconstruction, and anomaly detection. A dedicated treatment of multimodal fusion networks shows how imaging features can be integrated with genomic profiles and clinical records to yield more robust, context-aware predictions. To support clinical adoption, we outline post-hoc explainability More >

Jae Sung Son¹, Soo-Jin Kim^2,*

Congenital Heart Disease, Vol.20, No.4, pp. 421-440, 2025, DOI:10.32604/chd.2025.070250 - 18 September 2025

Abstract Background: Advancements in diagnostic tools, surgical techniques, and long-term management have significantly improved survival among individuals with congenital heart disease (CHD), leading to an evolving epidemiologic profile characterized by increasing procedural complexity and a growing adult CHD population. This study aimed to examine nationwide trends in CHD surgeries over a 17-year period, with a focus on temporal shifts in surgical volume, procedural complexity, and age-specific incidence. Methods: A total of 41,608 CHD surgeries and 85,417 surgical procedures performed between 2002 and 2018 were identified from a nationwide health insurance database. Temporal trends were evaluated using segmented… More >

Hande İştar^1,#,*, Buğra Harmandar¹, Melike Korkmaz Toker², Fulden Cantaş Türkiş³

Congenital Heart Disease, Vol.20, No.4, pp. 503-517, 2025, DOI:10.32604/chd.2025.068540 - 18 September 2025

Abstract Background: The neutrophil–lymphocyte ratio (NLR) is a simple, cost-effective marker of systemic inflammation. This study aims to evaluate the association between perioperative NLR and postoperative outcomes in pediatric patients undergoing congenital heart surgery with cardiopulmonary bypass (CPB). Methods: We retrospectively reviewed 70 patients under 18 years of age who underwent surgery between 2018 and 2023. NLR was measured preoperatively and on postoperative days (POD) 0, 1, 2, 3, and 6. Receiver operating characteristic analysis identified optimal cutoffs, and associations with postoperative outcomes were assessed. Results: The preoperative NLR cutoff of 1.14 (AUC = 0.75) was associated with More >

Stamatios Katsimperis^1,*, Lazaros Tzelves¹, Georgios Feretzakis², Themistoklis Bellos¹, Panagiotis Deligiannis¹, Andreas Skolarikos¹, Athanasios Papatsoris¹, Iraklis Mitsogiannis¹

Canadian Journal of Urology, Vol.32, No.4, pp. 271-282, 2025, DOI:10.32604/cju.2025.066395 - 29 August 2025

Abstract Background: Accurate complication reporting in endourology remains challenging, with the Clavien-Dindo Classification and Comprehensive Complication Index being the most commonly used systems. This study aimed to compare surgical outcomes and complication reporting in ureterolithotripsy (URL), percutaneous nephrolithotomy (PCNL), and extracorporeal shock wave lithotripsy (ESWL) using both systems. Methods: This prospective, single-center, non-interventional study included 473 patients undergoing URL, PCNL, or ESWL from October 2022 to October 2024. Demographic, stone-related, and procedural variables were recorded. Complications were classified using the CDC, and cumulative morbidity was assessed using CCI. Statistical analyses, including univariate and multivariate regression, were… More >