Lucas B. Vergamini, Pedro Z. Padovani, Nicholas Choi, Wilson R. Molina, Donald Neff, David A. Duchene, Emily Elliott, Colby Souders, Maxton Thoman, Bristol B. Whiles^*

Canadian Journal of Urology, Vol.33, No.4, pp. 967-975, 2026, DOI:10.32604/cju.2026.078800 - 21 August 2026

Abstract Objectives: In September 2024, Hurricane Helene caused extensive infrastructure damage in the United States, including severe disruption to a major Baxter sterile irrigation fluid manufacturing facility in North Carolina, leading to a nationwide shortage of sterile irrigation fluids used in surgical procedures. The objective of this study was to evaluate the impact of the nationwide sterile irrigation fluid shortage on urologic practice across the United States (U.S.) Methods: A descriptive, cross-sectional Research Electronic Data Capture (REDCap) survey was distributed to U.S. urologists. The questionnaire captured provider demographics, procedure delays, and practice/procedure modifications. Results: Ninety-five surgeons responded.… More >

Alberto Olivero^1,*, Sofia Giudici², Alberto Caviglia¹, Erika Palagonia¹, Marco Nizzardo³, Alberto Quistini³, Andrea Grasso⁴, Ofir Maltzman¹, Marco Colombo⁵, Stefano Tappero¹, Elio Mazzone¹, Paolo Dell’Oglio¹, Aldo Massimo Bocciardi¹, Antonio Galfano¹, Silvia Secco¹

Canadian Journal of Urology, Vol.33, No.4, pp. 959-965, 2026, DOI:10.32604/cju.2026.076804 - 21 August 2026

Abstract Background: Minimally invasive surgical techniques (MISTs) are becoming an increasingly popular outpatient treatment option for lower urinary tract symptoms. Although generally well-tolerated, MISTs may cause periprocedural discomfort. Virtual reality devices (VRDs) have been shown to reduce patient-reported pain during several procedures. This study aims to evaluate whether the use of VRD during MISTs could improve perioperative endovenous sedation needs of a VRD during MISTs in a case-control design. Methods: We retrospectively analyzed patient data from MISTs performed between January 2024 and July 2025 at a single referral center (ASST Grande Ospedale Metropolitano Niguarda, Milan, Italy).… More >

Liliana Guadagni¹, Marco Falcone^2,3,4, Lorenzo Cirigliano^2,5,*, Ilaria Ferro², Mirko Preto², Natalia Plamadeala², Martina Scavone², Emanuele Zupo², Paolo Gontero²

Canadian Journal of Urology, Vol.33, No.4, pp. 913-921, 2026, DOI:10.32604/cju.2026.076284 - 21 August 2026

Abstract Background: Testicular prosthesis implantation (TPI) is frequently performed as part of masculinizing genital gender-affirming surgery (GGAS), but complication and satisfaction data for assigned female at birth (AFAB) men remain limited. We report a single-centre experience assessing postoperative complications, explantation-free survival (EFS) and patient-reported satisfaction. Methods: We conducted a retrospective cohort study including all patients who underwent unilateral or bilateral transmasculine TPI (TM-TPI) from May 2007 to April 2025. Primary outcomes were postoperative complications (e.g., surgical-site infection, contamination, hematoma, migration, pain, extrusion) and EFS rate. Satisfaction was measured at 12 months using the 13-item Transmasculine Testicular… More >

Shih-Wei Chiang^1,2, Ming-Cheng Chen^2,3, Chang-Lin Lin², Yi-Lin Huang², Feng-Fan Chiang^2,4,*, Shun-Fa Yang^1,5,*

Oncology Research, Vol.34, No.9, 2026, DOI:10.32604/or.2026.085229 - 13 August 2026

Abstract Background: Anti-EGFR therapy is widely used as first-line treatment for RAS wild-type metastatic colorectal cancer (mCRC), particularly in patients with left-sided tumors. In liver-limited disease, maximizing tumor shrinkage may facilitate conversion to resectability; however, comparative real-world evidence among panitumumab, cetuximab, and bevacizumab remains limited. This study aimed to compare the clinical outcomes of these biologic agents in patients with RAS wild-type mCRC. Methods: We retrospectively analyzed 241 patients with RAS wild-type mCRC treated with first-line chemotherapy plus panitumumab (n = 76), cetuximab (n = 80), or bevacizumab (n = 85) between 2016 and 2024. Outcomes included depth of response… More >

Fan Yang^1,#, Xia Li^1,#, Zhiyuan Zhu^1,#, Shilin Wang^1,#, Zhongyuan Lu¹, Chao Yue², Leilei Duan¹, Xu Wang^1,*

Structural and Congenital Heart Disease, Vol.21, No.3, 2026, DOI:10.32604/schd.2026.075534 - 31 July 2026

Abstract Background: Early major adverse events (MAEs) after cardiac surgery are associated with substantial postoperative morbidity and mortality in infants with congenital heart disease (CHD). Early identification of patients at increased risk may facilitate timely intervention and optimize postoperative management. This study aimed to identify perioperative predictors of early MAEs and to develop a nomogram for individualized postoperative risk assessment. Methods: This single-center retrospective study included 766 infants with CHD who underwent cardiac surgery with cardiopulmonary bypass at Beijing Fuwai Hospital between January 2020 and December 2021. Early MAEs were defined as the occurrence of at least… More >

Giovanni Leuzzi^1,*, Michele Ferrari¹, Federica Sabia¹, Alessandro Pardolesi¹, Alessia Stanzi¹, Claudia Proto², Giuseppe Lo Russo², Arsela Prelaj², Monica Ganzinelli², Matteo Calderoni¹, Clarissa Uslenghi¹, Ugo Pastorino³, Piergiorgio Solli¹

Oncology Research, Vol.34, No.8, 2026, DOI:10.32604/or.2026.077158 - 16 July 2026

Abstract Backgrounds: Despite the availability of multimodal strategies, no universally accepted guidelines exist for the management of advanced Thymic Epithelial Tumors (TETs), particularly in locally advanced thymomas. The aim of this study was to evaluate the oncological and surgical outcomes of induction therapy (IT) followed by surgery in patients with Masaoka–Koga stage III–IVA TETs. To this end, we conducted a systematic review and meta-analysis assessing surgical-pathological and survival outcomes. Methods: Following Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines, a systematic search of PubMed, Embase, and the Cochrane Central Register of Controlled Trials was performed.… More > Graphic Abstract

Tyler Overholt Daniel^1,*, David Thole², Randy Casals³, Anthony Atala³, Steve Hodges³, Marc Colaco³

Canadian Journal of Urology, Vol.33, No.3, pp. 693-698, 2026, DOI:10.32604/cju.2026.074059 - 29 June 2026

Abstract Objectives: Day of surgery cancellations present several workflow challenges that result in delay of care for patients and revenue loss for physicians. This study aimed to further understand same-day pediatric urology surgical cancellations, and the authors assessed identifiable trends for quality improvement over a one-year time period. Methods: Same-day surgical cancellations were prospectively identified at a single tertiary care center, Atrium Health Wake Forest Baptist, from 01 October 2022 to 30 September 2023. Reasons for cancellation were recorded per the parent/legal guardian and categorized as an avoidable or unavoidable cause. Demographic data, surgical rescheduling, and… More >

Sin Woo Lee^*, Seung-Kwon Choi

Canadian Journal of Urology, Vol.33, No.3, pp. 527-535, 2026, DOI:10.32604/cju.2025.073355 - 29 June 2026

Abstract Background: Postoperative infections are an emerging concern in endourology. This study reports an outbreak of urinary tract infections associated with Pseudomonas aeruginosa (PA) in patients who underwent stone removal surgery using flexible ureteroscopy (FURS) at Seoul Medical Center. Methods: Between August and December 2024, five patients who underwent FURS performed by the same surgeon developed postoperative febrile episodes requiring further treatment. Urine cultures from four patients revealed an outbreak of multidrug-resistant PA, prompting environmental cultures and an inspection of the instrument reprocessing procedures led by the hospital’s infection control department. Results: Although PA was not isolated from… More >

Sezgin Yeni^1,*, Hakan Kilicarslan², Bertan Tanrıbuyurdu², Levent Turan², Hatice Ortac³, Onur Kaygisiz²

Canadian Journal of Urology, Vol.33, No.3, pp. 635-642, 2026, DOI:10.32604/cju.2026.072974 - 29 June 2026

Abstract Objectives: Retrograde intrarenal surgery (RIRS) has become an increasingly preferred minimally invasive option for the management of kidney stones. However, postoperative pain remains a major clinical concern that may adversely affect patient comfort and recovery. This study aimed to evaluate whether intraluminal administration of lidocaine at the end of RIRS could effectively reduce postoperative pain and analgesic requirements. Methods: A total of 61 patients who underwent RIRS between March and July 2024 were evaluated. Four patients were excluded due to residual stones, and five due to a history of cardiac arrhythmia, leaving 52 patients for… More >

Yubao Liu, Haifeng Song, Zheng Xu, Weiguo Hu, Bo Xiao, Gang Zhang, Boxing Su, Bixiao Wang, Jianxing Li^*

Canadian Journal of Urology, Vol.33, No.3, pp. 685-692, 2026, DOI:10.32604/cju.2025.070417 - 29 June 2026

Abstract Objective: The pressure fluctuations during retrograde intrarenal surgery (RIRS) can cause related complications, so precise monitoring and control of intrarenal pressure (IRP) play an important role. This study aimed to assess the clinical value of a Chinese-made disposable pressure-measuring flexible ureteroscope in monitoring IRP during RIRS for upper urinary tract stones <2 cm, and analyze factors affecting IRP. Methods: In this prospective single-arm study, 35 patients (38 renal units) underwent RIRS. Mean age was 42.3 ± 6.1 years, body mass index (BMI) 24.2 ± 2.6 kg/m², and maximum stone diameter 1.6 ± 0.4 cm. Stones… More >