Ruikang Ma1,2, Ziying Huang1, Zexiu Zhang3, Ruohui Lu4, Menghan Li1, Zhiyi Luo3, Mengni Li5, Pengyue Zhang3, Xiaohong Lin3, Guozhuang Zhang1,*, Linlin Dong1,*
Phyton-International Journal of Experimental Botany, Vol.94, No.11, pp. 3721-3748, 2025, DOI:10.32604/phyton.2025.072062
- 01 December 2025
Abstract Dendrobium officinale (DO) is a well-recognized medicinal and edible plant with a long history of application in traditional medicinal practices across China and Southeast Asia. Recent studies have demonstrated that DO is abundant in diverse bioactive compounds, including polysaccharides (DOP), flavonoids, alkaloids, and bibenzyls thought to exert a range of pharmacological effects, such as anti-tumor and immunomodulatory effects. However, our comprehensive understanding of two key aspects—pharmacological functions and biosynthetic mechanisms—of DO’s major constituents remains limited, especially when considered within the clinical contexts of traditional use. To address this gap, this study reviews DO’s historical applications, clinical effects, and… More >
Graphic Abstract