Naglaa. F. Soliman^1,*, Samia M. Abd Alhalem², Walid El-Shafai², Salah Eldin S. E. Abdulrahman³, N. Ismaiel³, El-Sayed M. El-Rabaie², Abeer D. Algarni¹, Fatimah Algarni⁴, Fathi E. Abd El-Samie^1,2

Intelligent Automation & Soft Computing, Vol.33, No.1, pp. 103-116, 2022, DOI:10.32604/iasc.2022.017691

Abstract Identifying and classifying Deoxyribonucleic Acid (DNA) sequences and their functions have been considered as the main challenges in bioinformatics. Advances in machine learning and Deep Learning (DL) techniques are expected to improve DNA sequence classification. Since the DNA sequence classification depends on analyzing textual data, Bidirectional Long Short-Term Memory (BLSTM) algorithms are suitable for tackling this task. Generally, classifiers depend on the patterns to be processed and the pre-processing method. This paper is concerned with a new proposed classification framework based on Frequency Chaos Game Representation (FCGR) followed by Discrete Wavelet Transform (DWT) and BLSTM. Firstly, DNA strings are transformed… More >

Naglaa. F. Soliman^1,*, Samia M. Abd-Alhalem², Walid El-Shafai², Salah Eldin S. E. Abdulrahman³, N. Ismaiel³, El-Sayed M. El-Rabaie², Abeer D. Algarni¹, Fatimah Algarni⁴, Amel A. Alhussan⁵, Fathi E. Abd El-Samie^1,2

Intelligent Automation & Soft Computing, Vol.32, No.3, pp. 1881-1891, 2022, DOI:10.32604/iasc.2022.017683

Abstract Recently, deep learning has opened a remarkable research direction in the track of bioinformatics, especially for the applications that need classification and regression. With deep learning techniques, DNA sequences can be classified with high accuracy. Firstly, a DNA sequence should be represented, numerically. After that, DNA features are extracted from the numerical representations based on deep learning techniques to improve the classification process. Recently, several architectures have been developed based on deep learning for DNA sequence classification. Convolutional Neural Network (CNN) and Recurrent Neural Network (RNN) are the default deep learning architectures used for this task. This paper presents a… More >