Haytham A. Ali^1,2,*, Hiroyuki Kudo¹

CMC-Computers, Materials & Continua, Vol.73, No.2, pp. 3741-3756, 2022, DOI:10.32604/cmc.2022.029394

Abstract This paper proposes a new level-set-based shape recovery approach that can be applied to a wide range of binary tomography reconstructions. In this technique, we derive generic evolution equations for shape reconstruction in terms of the underlying level-set parameters. We show that using the appropriate basis function to parameterize the level-set function results in an optimization problem with a small number of parameters, which overcomes many of the problems associated with the traditional level-set approach. More concretely, in this paper, we use Gaussian functions as a basis function placed at sparse grid points to represent the parametric level-set function and… More >

Jia Qin^1,2,3,4,5, Lin An^1,2,3,4,5,*

Molecular & Cellular Biomechanics, Vol.19, No.3, pp. 151-157, 2022, DOI:10.32604/mcb.2022.018578

Abstract Myopia is a common ophthalmic deficiency. The structure and function of choroid layer is assumed to be associated with myopia. In this study, a laboratory developed spectral domain optical coherence tomography scanning system is used to image human eyes. The axial resolution of the system is about 7 μm, and the acquisition rate is 100 kHz. Firstly, a cross-sectional image was acquired by averaging 100 images from imaging posterior segment of each eye. The choroid thickness was measured by 11 discrete points. The average thickness of normal human eyes was (0.296 ± 0.126) mm, whereas the average choroid thickness of… More >

Joddat Fatima^1,*, Amina Jameel², Muhammad Usman Akram³, Adeel Muzaffar Syed¹, Malaika Mushtaq³

Intelligent Automation & Soft Computing, Vol.34, No.3, pp. 1489-1504, 2022, DOI:10.32604/iasc.2022.025935

Abstract The long twisted fragile tube, termed as spinal cord, can be named as the second vital organ of Central Nervous System (CNS), after brain. In human anatomy, all crucial life activities are controlled by CNS. The spinal cord does not only control the flow of information from the brain to rest of the body, but also takes charge of our reflexes control and the mobility of body. It keeps the body upright and acts as the main support for the flesh and bones. Spine deformity can occur by birth, due to aging, injury or spine surgery. In this research article,… More >

S. Priyadarsini^1,*, Carlos Andrés Tavera Romero², Abolfazl Mehbodniya³, P. Vidya Sagar⁴, Sudhakar Sengan⁵

Computer Systems Science and Engineering, Vol.43, No.3, pp. 1057-1068, 2022, DOI:10.32604/csse.2022.024788

Abstract In the recent days, the segmentation of Liver Tumor (LT) has been demanding and challenging. The process of segmenting the liver and accurately spotting the tumor is demanding due to the diversity of shape, texture, and intensity of the liver image. The intensity similarities of the neighboring organs of the liver create difficulties during liver segmentation. The manual segmentation does not provide an accurate segmentation because the results provided by different medical experts can vary. Also, this manual technique requires a large number of image slices and time for segmentation. To solve these issues, the Fully Automatic Segmentation (FAS) technique… More >

R. Vidhya^1,*, T. T. Mirnalinee²

Intelligent Automation & Soft Computing, Vol.34, No.2, pp. 911-925, 2022, DOI:10.32604/iasc.2022.025060

Abstract Computer tomography (CT) scan images can provide more helpful diagnosis information regarding the lung cancers. Many machine learning and deep learning algorithms are formulated using CT input scan images for the improvisation in diagnosis and treatment process. But, designing an accurate and intelligent system still remains in darker side of the research side. This paper proposes the novel classification model which works on the principle of fused features and optimized learning network. The proposed framework incorporates the principle of saliency maps as a first tier segmentation, which is then fused with deep convolutional neural networks to improve the classification maps… More >

Nabila Mansouri^1,2,*, Khalid Sultan³, Aakash Ahmad⁴, Ibrahim Alseadoon⁴, Adal Alkhalil⁴

Intelligent Automation & Soft Computing, Vol.34, No.2, pp. 1247-1264, 2022, DOI:10.32604/iasc.2022.025046

Abstract The outbreak of novel Coronavirus COVID-19, an infectious disease caused by the SARS-CoV-2 virus, has caused an unprecedented medical, economic, and social emergency that requires data-driven intelligence and decision support systems to counter the subsequent pandemic. Data-driven models and intelligent systems can assist medical researchers and practitioners to identify symptoms of COVID-19 infection. Several solutions based on medical image processing have been proposed for this purpose. However, the most shortcoming of hand craft image processing systems is the lower provided performances. Hence, for the first time, the proposed solution uses a deep learning model that is applied to Computed Tomography… More >

S. Jeevitha^1,*, K. Valarmathi²

Intelligent Automation & Soft Computing, Vol.34, No.2, pp. 1123-1139, 2022, DOI:10.32604/iasc.2022.024746

Abstract Pulmonary Embolism is a blood clot in the lung which restricts the blood flow and reduces blood oxygen level resulting in mortality if it is untreated. Further, pulmonary embolism is evidenced prominently in the segmental and sub-segmental regions of the computed tomography angiography images in COVID-19 patients. Pulmonary embolism detection from these images is a significant research problem in the challenging COVID-19 pandemic in the venture of early disease detection, treatment, and prognosis. Inspired by several investigations based on deep learning in this context, a two-stage framework has been proposed for pulmonary embolism detection which is realized as a segmentation… More >

WEIYU CHEN^1,2, MUHSIN H. YOUNIS³, ZHONGKUO ZHAO^1,*, WEIBO CAI^3,*

BIOCELL, Vol.46, No.8, pp. 1789-1801, 2022, DOI:10.32604/biocell.2022.018197

Abstract The knowledge of interactions among functional proteins helps researchers understand disease mechanisms and design potential strategies for treatment. As a general approach, the fluorescent and affinity tags were employed for exploring this field by labeling the Protein of Interest (POI). However, the autofluorescence and weak binding strength significantly reduce the accuracy and specificity of these tags. Conversely, HaloTag, a novel self-labeling enzyme (SLE) tag, could quickly form a covalent bond with its ligand, enabling fast and specific labeling of POI. These desirable features greatly increase the accuracy and specificity, making the HaloTag a valuable system for various applications ranging from… More >

S. Priyadarsini^1,*, Carlos Andrés Tavera Romero², M. Mrunalini³, Ganga Rama Koteswara Rao⁴, Sudhakar Sengan⁵

Intelligent Automation & Soft Computing, Vol.33, No.3, pp. 1517-1530, 2022, DOI:10.32604/iasc.2022.024786

Abstract A classification system is used for Benign Tumors (BT) and Malignant Tumors (MT) in the abdominal liver. Computed Tomography (CT) images based on enhanced RGS is proposed. Diagnosis of liver diseases based on observation using liver CT images is essential for surgery and treatment planning. Identifying the progression of cancerous regions and Classification into Benign Tumors and Malignant Tumors are essential for treating liver diseases. The manual process is time-consuming and leads to intra and inter-observer variability. Hence, an automatic method based on enhanced region growing is proposed for the Classification of Liver Tumors (LT). To enhance the Liver Region… More >

Xiaorui Zhang^1,2,3,*, Jie Zhou², Wei Sun^3,4, Sunil Kumar Jha⁵

CMC-Computers, Materials & Continua, Vol.72, No.1, pp. 1123-1137, 2022, DOI:10.32604/cmc.2022.024589

Abstract The key to preventing the COVID-19 is to diagnose patients quickly and accurately. Studies have shown that using Convolutional Neural Networks (CNN) to analyze chest Computed Tomography (CT) images is helpful for timely COVID-19 diagnosis. However, personal privacy issues, public chest CT data sets are relatively few, which has limited CNN's application to COVID-19 diagnosis. Also, many CNNs have complex structures and massive parameters. Even if equipped with the dedicated Graphics Processing Unit (GPU) for acceleration, it still takes a long time, which is not conductive to widespread application. To solve above problems, this paper proposes a lightweight CNN classification… More >