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    ARTICLE

    Serum Level of Tumor-Specific Growth Factor in Patients with Cervical Cancer and Its Potential Prognostic Role

    Yao Wu1,2,#, Bin Qu1,#, Haoming Shen1, Hongyu Deng1, Faqin Tang1,*

    Oncologie, Vol.24, No.3, pp. 499-512, 2022, DOI:10.32604/oncologie.2022.024951

    Abstract Background: Tumor-specific growth factor (TSGF) is associated with invasion and metastasis of various malignancies and adverse clinical outcomes. TSGF is also highly expressed in cervical cancer (CC), but its clinical value is unclear. Materials and Methods: Serum samples from malignancies, including CC, non-Hodgkin’s lymphoma (NHL), nasopharyngeal carcinoma (NPC), colorectal cancer (CRC), lung cancer (LCA), ovarian cancer (OC), breast cancer (BC), gastric carcinoma (GC), and pancreatic cancer (PC) were collected, and TSGF was detected using a chemiluminescence assay. The patients with CC were followed-up over five years, and their clinicopathological parameters were analyzed. Meanwhile, the pre- and post-treatment TSGF levels of… More >

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