Akisue Kuramoto^1,*, Hitoshi Kimura², Norio Inou²

Molecular & Cellular Biomechanics, Vol.16, Suppl.2, pp. 126-126, 2019, DOI:10.32604/mcb.2019.08127

Abstract Comfortable bedding is usually designed subjectively because of the difficulty in performing a quantitative evaluation. This paper proposes a quantitative evaluation method of comfortableness of beddings. The bedding shape determining how comfortable an individual may feel in using it depends on the body shape and normal posture of individuals. The internal physical load is expected to relate to the comfortableness of bedding. However, only a few quantitative discussions exist on the relation between the comfortableness of bedding and physical load. This study proposes a new evaluation method of physical load in a relaxed posture. The… More >

Lulu Wang^1,*

Molecular & Cellular Biomechanics, Vol.16, Suppl.2, pp. 125-125, 2019, DOI:10.32604/mcb.2019.07101

Abstract Early diagnosis of stroke with timely treatment could reduce adult permanent disability significantly [1]. Conventional medical imaging tools such as X-ray, ultrasound, computed tomography (CT), magnetic resonance imaging (MRI) and positron emission tomography (PET) have been widely used for diagnosis of brain disease. However, each of these methods has some limitations. X-ray imaging produces harmful radiation to the human body and challenging to identify early-stage abnormal tissue due to the relatively small dielectric proprieties contrast between the healthy tissue and abnormal tissue at X-ray frequencies [2]. PET provides useful information about soft tissues, but it… More >

Meng-Wei Lin¹, Feng Yang^1,*

Molecular & Cellular Biomechanics, Vol.16, Suppl.2, pp. 123-124, 2019, DOI:10.32604/mcb.2019.07343

Abstract This article has no abstract. More >

Chien-Chi Liu¹, Sai-Wei Yang^1,*, Tsui-Fen Yang²

Molecular & Cellular Biomechanics, Vol.16, Suppl.2, pp. 120-122, 2019, DOI:10.32604/mcb.2019.07150

Abstract Scoliosis is the most common type of spinal deformity of the young adults, and women outnumber men about 10:1 [1], in which the Adolescent Idiopathic Scoliosis (AIS) is up to 90% for ages 10 to 16year-old teenagers [2]. Studies revealed that due to the 3-dimensional musculoskeletal deformities, the AIS subjects to the dynamic postural instability including vestibular and proprioception disorders [3-5]. Dynamic postural Balance is monitored by integration of cortical modulation and somatosensory response [6], and the either motor or sensory impairment lead to balance dysfunction as well as pathologic gait. Studies revealed that the… More >

Yao Guo¹, Yijiang Song², Yu Zhang¹, Li Yang^1,*

Molecular & Cellular Biomechanics, Vol.16, Suppl.2, pp. 119-119, 2019, DOI:10.32604/mcb.2019.07134

Abstract Osteoarthritis (OA), with its high disability and mortality rate, is the most common arthritis throughout the world [1]. Exposure of articular cartilage to excessive mechanical stress is deeply involved in the pathogenesis of osteoarthritis (OA) [2,3]. However, the mechanism of how mechanical stress causes cartilage degradation is not clear yet. Here we report that bioinformatics-based integrative analyses can assist in the study of mechanisms modulated by mechanical stress within OA pathology, and we reveal that B-cell Translocation Gene 2 (BTG2) can be a mechanosensitive gene involved in OA development. We obtained OA-associated differentially expressed genes… More >

Lianhong Pan¹, Li Yang^2,*

Molecular & Cellular Biomechanics, Vol.16, Suppl.2, pp. 118-118, 2019, DOI:10.32604/mcb.2019.07133

Abstract Osteoarthritis (OA) is a chronic joint bone disease which always leads to the dysfunction and disability of arthritis. Synovial inflammation plays an important role in the pathogenesis and progress of OA which can secrete large amounts of inflammatory cytokines. There is an urgent need to find safe and effective drugs that can reduce the inflammation and regulate the pathogenesis of cytokines of the OA disease. Icariin, a traditional Chinese herbal medicine, is the major pharmacological active component of herb Epimedium. This study we investigated the influence of icariin on the main cells in synovium-osteoarthritis fibroblast-like synoviocytes… More >

Zhongzheng Wang^1,2, Fei Tian³, Shaobai Wang³, Songtao Ai², Tsung-Yuan Tsai^1,*

Molecular & Cellular Biomechanics, Vol.16, Suppl.2, pp. 116-117, 2019, DOI:10.32604/mcb.2019.07690

Abstract This article has no abstract. More >

Hsiang-Wen Huang¹, Ting-Wei Kuo¹, Chi-Long Lee¹, Yan-Ting Lin¹, Yan-Ying Ju², Chih-Hsiu Cheng^1,*

Molecular & Cellular Biomechanics, Vol.16, Suppl.2, pp. 113-115, 2019, DOI:10.32604/mcb.2019.07509

Abstract Wheelchair basketball is mainly designed for people who are physically challenged with permanent lower body disabilities. Free throw execution is one of the basic skills and could represent the preferred shooting mechanics so as to examine the overall shooting mechanics in basketball players. It requires the body to act as a kinetic chain to summate energy from the wheelchair to the upper extremity for the coordinated movements. Researchers have shown that the kinetic chain of the wheelchair basketball athletes could be affected by the kinematic parameters such as the release velocity and shooting angle [1-3].… More >

Xiaofei Wang^1,2,*, Yubo Fan^1,2

Molecular & Cellular Biomechanics, Vol.16, Suppl.2, pp. 112-112, 2019, DOI:10.32604/mcb.2019.07053

Abstract Accommodation is the ability of the eye to adjust its lens thickness to alter the refractive power through the contraction of ciliary muscles. The loss of accommodation ability due to aging leads to presbyopia, a condition in which the eye is unable to focus on near objects. Glaucoma is a disease that vision is impaired due to damage of the retinal ganglion cell at the optic nerve head (ONH) region, which is the leading cause of irreversible blindness worldwide. The biomechanical theory of glaucoma suggests that the deformations of ONH tissues could (directly or indirectly)… More >

Yongqiang Li^1,#, Changxin Lai^1,#, Chengchen Zhang², Alexa Singer¹, Suhao Qiu¹, Boming Sun², Michael S. Sacks³, Yuan Feng^1,*

Molecular & Cellular Biomechanics, Vol.16, Suppl.2, pp. 111-111, 2019, DOI:10.32604/mcb.2019.07098

Abstract Surgeries such as implantation of deep brain stimulation devices require accurate placement of devices within the brain. Because placement affects performance, image guidance and robotic assistance techniques have been widely adopted. These methods require accurate prediction of brain deformation during and following implantation. In this study, a magnetic resonance (MR) image-based finite element (FE) model was proposed by using a coupled Eulerian-Lagrangian method. Anatomical accuracy was achieved by mapping image voxels directly to the volumetric mesh space. The potential utility was demonstrated by evaluating the effect of different surgical approaches on the deformation of the… More >