Vol.44, No.2, 2020, pp.167-174, doi:10.32604/biocell.2020.09023
OPEN ACCESS
REVIEW
Current status of gene therapy in melanoma treatment
  • YONGLU WANG1,2,*, WEI YOU1, XUEMING LI3,4,*
1 College of Pharmacy, Nanjing Tech University, Nanjing, China
2 College of Pharmacy and Nutrition, University of Saskatchewan, Saskatoon, Canada
3 Nanjing Bestform Pharmaceutical Technology Co., Ltd., Nanjing, China
4 Postgraduate Department, Nanjing Tech University, Nanjing, China
* Address correspondence to: Yonglu Wang, yonglu_wang777@163.com; Xueming Li, xuemingli@njtech.edu.cn
Received 04 November 2019; Accepted 16 April 2020; Issue published 27 May 2020
Abstract
Melanoma is the deadliest type of skin cancer and which has a high ability of metastasis. Surgery is an effective method to treat I or II stage melanoma patients. However, there are few treatment options for metastatic melanoma. Gene therapy is one of the attractive options and is considered as the future direction for treating melanoma. This review mainly discusses the properties and challenges of the various gene therapies in melanoma, especially the delivery systems and gene targeting.
Keywords
Gene therapy, Melanoma, Viral delivery system, Nanoparticles
Cite This Article
WANG, Y., YOU, W., LI, X. (2020). Current status of gene therapy in melanoma treatment. BIOCELL, 44(2), 167–174.
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